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Brainomix vs Circle Cardiovascular Imaging

Circle's cvi42 is a cardiac imaging platform. It covers volumes, strain, mapping, calcium scoring and plaque quantification on MR and CT, and the vendor names integrated solutions with GE Healthcare and Siemens Healthineers. A cardiology imaging lab is the natural buyer.

Brainomix is built around the stroke pathway. Its e-ASPECTS, e-CTP and e-MRI modules each have their own FDA decision, and results flow back into PACS as annotated DICOM series or PDF reports.

The two meet in acute stroke imaging. Circle's pages name StrokeSENS for ASPECTS (K250221, July 2025), large vessel occlusion detection and multiphase CTA perfusion. Brainomix's pages describe e-CTP with mismatch ratio and Tmax measures, and e-MRI with DWI-FLAIR mismatch. For a stroke center that wants CT perfusion and MRI mismatch tools, Brainomix is the pick and Circle is second.

A hospital whose cardiac MR lab is the bigger workload and whose stroke need stops at ASPECTS on CT can take Circle for both jobs.

Radiology · Reviewed November 2, 2026

Brainomix logo

Brainomix

by Brainomix Limited · founded 2012

FDA-cleared AI scoring and large vessel occlusion flagging for stroke CT, CTA, CTP and MRI, plus CT lung quantification.

Circle Cardiovascular Imaging logo

Circle Cardiovascular Imaging

by Circle Cardiovascular Imaging Inc. · founded 2007

cvi42 cardiac MR and CT software with FDA-cleared AI coronary plaque analysis and StrokeSENS acute stroke tools.

When to pick each one

Brainomix

  • e-ASPECTS decisions in February 2023 and February 2025
  • e-CTP and e-MRI perfusion and DWI-FLAIR modules
  • Results return to PACS as annotated DICOM or PDF
Read the full Brainomix review

Circle Cardiovascular Imaging

  • Cardiac MR and CT analysis in one platform
  • Coronary plaque software cleared October 2025
  • Named GE Healthcare and Siemens Healthineers integrations
Read the full Circle Cardiovascular Imaging review

Score

Each row shows points earned of points available under the published rubric.

Brainomix

64of 100

Top-ranked

Circle Cardiovascular Imaging

42of 100

Competitive
Score by dimension for Brainomix and Circle Cardiovascular Imaging
DimensionBrainomixCircle Cardiovascular ImagingDifference
FDA clearance18 / 1818 / 180
HIPAA / SOC2 / BAA0 / 100 / 100
EHR integrations (count)0 / 4.20 / 4.20
Top-3 EHR coverage (Epic / Oracle / Athena)0 / 2.40 / 2.40
Peer-reviewed papers18.2 / 18.20 / 18.2+18.2
RCT / meta-analysis / systematic review0 / 7.80 / 7.80
Funding & adoption signal8.4 / 128.4 / 120
Pricing transparency2.5 / 52.5 / 50
Years in market6 / 66 / 60

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How scores are computed

Pricing

Brainomix

TierMonthlyAnnualNotes
Enterprisen/an/aNo public price.

Circle Cardiovascular Imaging

TierMonthlyAnnualNotes
Enterprisen/an/aNo public price.

Evidence

Brainomix

FDA decisions

Show 8 more

Peer-reviewed

5 PubMed records name Brainomix.

Circle Cardiovascular Imaging

FDA decisions

Show 7 more

Compliance and integrations

Documented from each vendor’s own pages.

SpecBrainomixCircle Cardiovascular Imaging
Free tierNo / unverifiedNo / unverified
HIPAANo / unverifiedNo / unverified
SOC 2 Type IINo / unverifiedNo / unverified
EHR integrationsNot specifiedNot specified
Founded20122007
HQGBCA

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Common questions

Open the full radiology comparison

Acute-care triage, mammography screening, CCTA plaque analysis, mobile MRI. 30+ FDA-cleared platforms across stroke, oncology, cardiac. Enterprise sales only — we compared what's deployed where.