Butterfly Network vs Eyenuk
Two sets of accuracy figures sit behind EyeArt. The Eyenuk home page claims 96% sensitivity and 88% specificity for more than mild diabetic retinopathy, while Eyenuk's 2023 press release on trial NCT04984200 gives 94.4% and 91.1%. The FDA record shows K200667 (August 2020) and K223357 (June 2023), and the FAQ lists Canon CR-2 AF, Canon CR-2 Plus AF and Topcon NW400 cameras. The FAQ also says EyeArt returns a DR level and report with no physician overread, that it is integrated with multiple major EHRs including Epic, and that billing runs under CPT 92229.
A diabetes clinic grading fundus photographs shops for Eyenuk. An ophthalmology practice weighing a pocket probe shops for Butterfly, and a 2024 Indian Journal of Ophthalmology study compared the iQ+ with B-scan for retinal detachment.
Radiology · Reviewed November 2, 2026
Butterfly Network
by Butterfly Network, Inc.
Butterfly iQ handheld whole-body ultrasound probe line, with FDA-cleared AI tools for bladder volume and gestational age.
Eyenuk
by Eyenuk, Inc.
EyeArt is FDA-cleared autonomous AI that grades diabetic retinopathy from retinal photos, with no physician overread needed.
When to pick each one
Butterfly Network
- iQ+ compared with B-scan for retinal detachment
- Probe pairs with compatible iPhone or Android
Eyenuk
- Two 510(k)s, K200667 and K223357
- FAQ says no physician overread needed
- FAQ names Epic among integrated EHRs
Score
Each row shows points earned of points available under the published rubric.
Butterfly Network
66of 100
Eyenuk
71of 100
| Dimension | Butterfly Network | Eyenuk | Difference |
|---|---|---|---|
| FDA clearance | 18 / 18 | 18 / 18 | 0 |
| HIPAA / SOC2 / BAA | 6 / 10 | 10 / 10 | -4 |
| EHR integrations (count) | 0 / 4.2 | 0 / 4.2 | 0 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 0 / 2.4 | 0 / 2.4 | 0 |
| Peer-reviewed papers | 12.7 / 18.2 | 18.2 / 18.2 | -5.5 |
| RCT / meta-analysis / systematic review | 7.8 / 7.8 | 7.8 / 7.8 | 0 |
| Funding & adoption signal | 8.4 / 12 | 3 / 12 | +5.4 |
| Pricing transparency | 2.5 / 5 | 2.5 / 5 | 0 |
| Years in market | 0 / 6 | 0 / 6 | 0 |
Scroll horizontally to see every column.
Pricing
Butterfly Network
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Butterfly iQ3 device | n/a | n/a | Device price, 3-year warranty. Shown with a dollar sign on the page, currency not otherwise stated. |
| Butterfly iQ+ device | n/a | n/a | Device price, 1-year warranty. Also stated as starts at $2,699 in the FAQ. |
| Core Technology membership | n/a | n/a | Plus probe. 1 seat, 2 probes online. |
| Advanced Technology membership | n/a | n/a | Plus probe. Adds Doppler modes, iQ Slice, iQ Fan, Biplane, Needle Viz and the AI tools Auto Bladder Volume and Auto B-Line Counter. |
| Advanced Technology one-time | n/a | n/a | Plus probe. Software access guaranteed for 5 years, no recurring fees required. |
Eyenuk
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. |
Evidence
Butterfly Network
FDA decisions
K252148 (opens in new tab)510(k)2026-03-27
Butterfly Gestational Age Tool
K200980 (opens in new tab)510(k)2020-06-11
Auto 3D Bladder Volume Tool
Peer-reviewed
4 PubMed records name Butterfly Network.
- Comparison of in-person versus virtual ultrasound instruction for pediatric residents. (opens in new tab)
- Comparison of Six Handheld Ultrasound Devices by Pediatric Point of Care Ultrasound (POCUS) Experts. (opens in new tab)
- Breast assessment using next generation handheld ultrasound device based on silicon chips: a pilot study in senology. (opens in new tab)
Eyenuk
FDA decisions
K223357 (opens in new tab)510(k)2023-06-16
EyeArt v2.2.0
K200667 (opens in new tab)510(k)2020-08-03
EyeArt
Peer-reviewed
5 PubMed records name Eyenuk.
- Diagnostic Accuracy of the EyeArt Artificial Intelligence System for Diabetic Retinopathy: A Systematic Review and Meta-Analysis. (opens in new tab)
- A pilot cost-analysis study comparing AI-based EyeArt® and ophthalmologist assessment of diabetic retinopathy in minority women in Oslo, Norway. (opens in new tab)
- [Use of Artificial Intelligence in Diabetic Retinopathy Screening: Experience in a Health Service in Santiago, Chile]. (opens in new tab)
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | Butterfly Network | Eyenuk |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Not specified | Not specified |
| Founded | n/a | n/a |
| HQ | n/a | US |
Scroll horizontally to see both columns.
Common questions
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