Butterfly Network vs HeartFlow
Heartflow trades on Nasdaq as HTFL. Its 10-K puts 2025 revenue at $176.0M, of which FFRct was 98%, and describes revenue as pay-per-use. Plaque Analysis had 489 US accounts at the end of 2025, and processing runs in the vendor's cloud from a coronary CT angiogram. Its first FFRct clearance was a De Novo, DEN130045, in November 2014, and later versions and Plaque Analysis went through 510(k). Heartflow's homepage shows no price.
Butterfly's iQ3 trade-in credit runs up to $1,500 (currency not stated) with no end date. The vendor's Affirm example is $3,119 over 36 months at about $87 a month and 0% APR, credit-dependent, currency not stated. A service reading coronary CTAs for flow assessment and plaque quantification needs Heartflow, while a small cardiology practice buying its first handheld needs the probe.
Radiology · Reviewed November 2, 2026

Butterfly Network
by Butterfly Network, Inc.
Butterfly iQ handheld whole-body ultrasound probe line, with FDA-cleared AI tools for bladder volume and gestational age.

HeartFlow
by HeartFlow · founded 2007
Coronary CT angiogram analysis: CT-derived fractional flow reserve (FFRct), plaque analysis and a CCTA reading aid.
When to pick each one
Butterfly Network
- Trade-in credit up to $1,500, currency not stated
- Affirm example $87 monthly, currency not stated
HeartFlow
- FFRct and plaque analysis from coronary CTA
- Pay-per-use revenue model per the 10-K
- Nasdaq-listed as HTFL
Score
Each row shows points earned of points available under the published rubric.
Butterfly Network
66of 100
HeartFlow
66of 100
| Dimension | Butterfly Network | HeartFlow | Difference |
|---|---|---|---|
| FDA clearance | 18 / 18 | 18 / 18 | 0 |
| HIPAA / SOC2 / BAA | 6 / 10 | 0 / 10 | +6 |
| EHR integrations (count) | 0 / 4.2 | 0 / 4.2 | 0 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 0 / 2.4 | 0 / 2.4 | 0 |
| Peer-reviewed papers | 12.7 / 18.2 | 12.7 / 18.2 | 0 |
| RCT / meta-analysis / systematic review | 7.8 / 7.8 | 7.8 / 7.8 | 0 |
| Funding & adoption signal | 8.4 / 12 | 8.4 / 12 | 0 |
| Pricing transparency | 2.5 / 5 | 2.5 / 5 | 0 |
| Years in market | 0 / 6 | 6 / 6 | -6 |
Scroll horizontally to see every column.
Pricing
Butterfly Network
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Butterfly iQ3 device | n/a | n/a | Device price, 3-year warranty. Shown with a dollar sign on the page, currency not otherwise stated. |
| Butterfly iQ+ device | n/a | n/a | Device price, 1-year warranty. Also stated as starts at $2,699 in the FAQ. |
| Core Technology membership | n/a | n/a | Plus probe. 1 seat, 2 probes online. |
| Advanced Technology membership | n/a | n/a | Plus probe. Adds Doppler modes, iQ Slice, iQ Fan, Biplane, Needle Viz and the AI tools Auto Bladder Volume and Auto B-Line Counter. |
| Advanced Technology one-time | n/a | n/a | Plus probe. Software access guaranteed for 5 years, no recurring fees required. |
HeartFlow
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Per study | n/a | n/a | No public list price. The 10-K describes revenue as pay-per-use. |
Evidence
Butterfly Network
FDA decisions
K252148 (opens in new tab)510(k)2026-03-27
Butterfly Gestational Age Tool
K200980 (opens in new tab)510(k)2020-06-11
Auto 3D Bladder Volume Tool
Peer-reviewed
4 PubMed records name Butterfly Network.
- Comparison of in-person versus virtual ultrasound instruction for pediatric residents. (opens in new tab)
- Comparison of Six Handheld Ultrasound Devices by Pediatric Point of Care Ultrasound (POCUS) Experts. (opens in new tab)
- Breast assessment using next generation handheld ultrasound device based on silicon chips: a pilot study in senology. (opens in new tab)
HeartFlow
FDA decisions
K250902 (opens in new tab)510(k)2025-07-18
HeartFlow Analysis
K213857 (opens in new tab)510(k)2022-10-14
HeartFlow Analysis
K203329 (opens in new tab)510(k)2021-01-08
HeartFlow Analysis
K190925 (opens in new tab)510(k)2019-08-15
K182035 (opens in new tab)510(k)2018-12-06
Show 3 more
K161772 (opens in new tab)510(k)2016-08-24
K152733 (opens in new tab)510(k)2016-01-13
DEN130045 (opens in new tab)De Novo2014-11-26
FFRct
Peer-reviewed
2 PubMed records name HeartFlow.
- Prognostic value of CT-derived fractional flow reserve for major adverse cardiovascular events in patients with suspected or known coronary artery disease: a systematic review and meta-analysis. (opens in new tab)
- Diagnostic Performance of AI-enabled Plaque Quantification from Coronary CT Angiography Compared with Intravascular Ultrasound. (opens in new tab)
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | Butterfly Network | HeartFlow |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Not specified | Not specified |
| Founded | n/a | 2007 |
| HQ | n/a | US |
Scroll horizontally to see both columns.
Common questions
Open the full radiology comparison
Acute-care triage, mammography screening, CCTA plaque analysis, mobile MRI. 30+ FDA-cleared platforms across stroke, oncology, cardiac. Enterprise sales only — we compared what's deployed where.
