CureMetrix vs HeartFlow
A cardiology or CT service that reads coronary CT angiograms is the HeartFlow buyer. FFRct Analysis gives CT-derived fractional flow reserve, first authorized by De Novo in November 2014 with later versions cleared by 510(k). Plaque Analysis quantifies and characterizes plaque (510(k), October 2022), and Roadmap Analysis supports consistent CCTA reads. Processing runs in the vendor's cloud. The FY2025 10-K describes revenue as pay-per-use, and no list price is published. CureMetrix is the call for a breast imaging practice that screens with mammography and wants calcification quantification, and the vendor says cmAngio returns results in minutes. A coronary CT service should skip CureMetrix, which reads mammograms. A breast practice should skip HeartFlow, which starts from a coronary CT angiogram. The answer follows the scan the department already reads: coronary CT points to HeartFlow, screening mammograms to CureMetrix.
Radiology · Reviewed November 2, 2026
CureMetrix
by CureMetrix
AI for mammograms: cmAngio quantifies breast arterial calcification (FDA-cleared), cmTriage prioritizes screening exams.

HeartFlow
by HeartFlow · founded 2007
Coronary CT angiogram analysis: CT-derived fractional flow reserve (FFRct), plaque analysis and a CCTA reading aid.
When to pick each one
CureMetrix
- Quantifies breast arterial calcification on mammograms
- cmAngio V2.0 510(k) decided July 2026
- Exam suspicion scoring for the reading worklist
HeartFlow
- CT-derived FFR from coronary CT angiograms
- Plaque Analysis 510(k), October 2022
- Per-study billing, no published list price
Score
Each row shows points earned of points available under the published rubric.
CureMetrix
48of 100
HeartFlow
66of 100
| Dimension | CureMetrix | HeartFlow | Difference |
|---|---|---|---|
| FDA clearance | 18 / 18 | 18 / 18 | 0 |
| HIPAA / SOC2 / BAA | 0 / 10 | 0 / 10 | 0 |
| EHR integrations (count) | 0 / 4.2 | 0 / 4.2 | 0 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 0 / 2.4 | 0 / 2.4 | 0 |
| Peer-reviewed papers | 12.7 / 18.2 | 12.7 / 18.2 | 0 |
| RCT / meta-analysis / systematic review | 3.9 / 7.8 | 7.8 / 7.8 | -3.9 |
| Funding & adoption signal | 3 / 12 | 8.4 / 12 | -5.4 |
| Pricing transparency | 2.5 / 5 | 2.5 / 5 | 0 |
| Years in market | 0 / 6 | 6 / 6 | -6 |
Scroll horizontally to see every column.
Pricing
CureMetrix
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. The homepage shows none. |
HeartFlow
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Per study | n/a | n/a | No public list price. The 10-K describes revenue as pay-per-use. |
Evidence
CureMetrix
FDA decisions
K260980 (opens in new tab)510(k)2026-07-30
cmAngio V2.0
K250754 (opens in new tab)510(k)2025-04-10
cmAngio V1.6
K232367 (opens in new tab)510(k)2023-10-05
cmAngio V1.0
K183285 (opens in new tab)510(k)2019-03-08
cmTriage
Peer-reviewed
3 PubMed records name CureMetrix.
- A Novel Breast Arterial Calcification Age-Based Percentile Nomogram for the Incremental Prediction of Incidental Cardiovascular Events. (opens in new tab)
- Evaluation of an Artificial Intelligence System for Detection of Invasive Lobular Carcinoma on Digital Mammography. (opens in new tab)
- Multicenter, Multivendor Validation of an FDA-approved Algorithm for Mammography Triage. (opens in new tab)
HeartFlow
FDA decisions
K250902 (opens in new tab)510(k)2025-07-18
HeartFlow Analysis
K213857 (opens in new tab)510(k)2022-10-14
HeartFlow Analysis
K203329 (opens in new tab)510(k)2021-01-08
HeartFlow Analysis
K190925 (opens in new tab)510(k)2019-08-15
K182035 (opens in new tab)510(k)2018-12-06
Show 3 more
K161772 (opens in new tab)510(k)2016-08-24
K152733 (opens in new tab)510(k)2016-01-13
DEN130045 (opens in new tab)De Novo2014-11-26
FFRct
Peer-reviewed
2 PubMed records name HeartFlow.
- Prognostic value of CT-derived fractional flow reserve for major adverse cardiovascular events in patients with suspected or known coronary artery disease: a systematic review and meta-analysis. (opens in new tab)
- Diagnostic Performance of AI-enabled Plaque Quantification from Coronary CT Angiography Compared with Intravascular Ultrasound. (opens in new tab)
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | CureMetrix | HeartFlow |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Not specified | Not specified |
| Founded | n/a | 2007 |
| HQ | US | US |
Scroll horizontally to see both columns.
Common questions
Open the full radiology comparison
Acute-care triage, mammography screening, CCTA plaque analysis, mobile MRI. 30+ FDA-cleared platforms across stroke, oncology, cardiac. Enterprise sales only — we compared what's deployed where.
