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CureMetrix vs HeartFlow

A cardiology or CT service that reads coronary CT angiograms is the HeartFlow buyer. FFRct Analysis gives CT-derived fractional flow reserve, first authorized by De Novo in November 2014 with later versions cleared by 510(k). Plaque Analysis quantifies and characterizes plaque (510(k), October 2022), and Roadmap Analysis supports consistent CCTA reads. Processing runs in the vendor's cloud. The FY2025 10-K describes revenue as pay-per-use, and no list price is published. CureMetrix is the call for a breast imaging practice that screens with mammography and wants calcification quantification, and the vendor says cmAngio returns results in minutes. A coronary CT service should skip CureMetrix, which reads mammograms. A breast practice should skip HeartFlow, which starts from a coronary CT angiogram. The answer follows the scan the department already reads: coronary CT points to HeartFlow, screening mammograms to CureMetrix.

Radiology · Reviewed November 2, 2026

CureMetrix logo

CureMetrix

by CureMetrix

AI for mammograms: cmAngio quantifies breast arterial calcification (FDA-cleared), cmTriage prioritizes screening exams.

HeartFlow logo

HeartFlow

by HeartFlow · founded 2007

Coronary CT angiogram analysis: CT-derived fractional flow reserve (FFRct), plaque analysis and a CCTA reading aid.

When to pick each one

CureMetrix

  • Quantifies breast arterial calcification on mammograms
  • cmAngio V2.0 510(k) decided July 2026
  • Exam suspicion scoring for the reading worklist
Read the full CureMetrix review

HeartFlow

  • CT-derived FFR from coronary CT angiograms
  • Plaque Analysis 510(k), October 2022
  • Per-study billing, no published list price
Read the full HeartFlow review

Score

Each row shows points earned of points available under the published rubric.

CureMetrix

48of 100

Solid choice

HeartFlow

66of 100

Top-ranked
Score by dimension for CureMetrix and HeartFlow
DimensionCureMetrixHeartFlowDifference
FDA clearance18 / 1818 / 180
HIPAA / SOC2 / BAA0 / 100 / 100
EHR integrations (count)0 / 4.20 / 4.20
Top-3 EHR coverage (Epic / Oracle / Athena)0 / 2.40 / 2.40
Peer-reviewed papers12.7 / 18.212.7 / 18.20
RCT / meta-analysis / systematic review3.9 / 7.87.8 / 7.8-3.9
Funding & adoption signal3 / 128.4 / 12-5.4
Pricing transparency2.5 / 52.5 / 50
Years in market0 / 66 / 6-6

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How scores are computed

Pricing

CureMetrix

TierMonthlyAnnualNotes
Enterprisen/an/aNo public price. The homepage shows none.

HeartFlow

TierMonthlyAnnualNotes
Per studyn/an/aNo public list price. The 10-K describes revenue as pay-per-use.

Evidence

Compliance and integrations

Documented from each vendor’s own pages.

SpecCureMetrixHeartFlow
Free tierNo / unverifiedNo / unverified
HIPAANo / unverifiedNo / unverified
SOC 2 Type IINo / unverifiedNo / unverified
EHR integrationsNot specifiedNot specified
Foundedn/a2007
HQUSUS

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Common questions

Open the full radiology comparison

Acute-care triage, mammography screening, CCTA plaque analysis, mobile MRI. 30+ FDA-cleared platforms across stroke, oncology, cardiac. Enterprise sales only — we compared what's deployed where.