HeartFlow vs icometrix
HeartFlow analyzes coronary CT angiograms and icometrix quantifies brain MRI, so a hospital buys them for different services. HeartFlow's homepage lists FFRct Analysis, Plaque Analysis and Roadmap Analysis, and its 10-K describes revenue as pay-per-use. The homepage gives no price. HeartFlow serves a cardiac CT program deciding on revascularization. icometrix's home page says icobrain helps radiologists and neurologists compare and quantify brain MRI scans over time, with pages for multiple sclerosis, dementia, epilepsy, stroke and traumatic brain injury. Its newest openFDA decision is icobrain aria, K240712, dated November 7, 2024, for ARIA-E and ARIA-H on MRI. GE HealthCare announced an agreement to acquire icometrix on September 10, 2025, and GE's release says icobrain distribution is meant to cover all vendor MRI systems, which a memory clinic monitoring amyloid-targeting therapy on scanners from several makers would note.
Radiology · Reviewed November 2, 2026
When to pick each one
HeartFlow
- FFRct, plaque and Roadmap analysis on coronary CTA
- Cardiac CT programs deciding on revascularization
icometrix
- Brain MRI volumetry across MS, dementia and epilepsy
- icobrain aria, K240712, for ARIA-E and ARIA-H
Score
Each row shows points earned of points available under the published rubric.
HeartFlow
66of 100
icometrix
68of 100
| Dimension | HeartFlow | icometrix | Difference |
|---|---|---|---|
| FDA clearance | 18 / 18 | 18 / 18 | 0 |
| HIPAA / SOC2 / BAA | 0 / 10 | 0 / 10 | 0 |
| EHR integrations (count) | 0 / 4.2 | 0 / 4.2 | 0 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 0 / 2.4 | 0 / 2.4 | 0 |
| Peer-reviewed papers | 12.7 / 18.2 | 18.2 / 18.2 | -5.5 |
| RCT / meta-analysis / systematic review | 7.8 / 7.8 | 3.9 / 7.8 | +3.9 |
| Funding & adoption signal | 8.4 / 12 | 8.4 / 12 | 0 |
| Pricing transparency | 2.5 / 5 | 2.5 / 5 | 0 |
| Years in market | 6 / 6 | 6 / 6 | 0 |
Scroll horizontally to see every column.
Pricing
HeartFlow
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Per study | n/a | n/a | No public list price. The 10-K describes revenue as pay-per-use. |
icometrix
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. |
Evidence
HeartFlow
FDA decisions
K250902 (opens in new tab)510(k)2025-07-18
HeartFlow Analysis
K213857 (opens in new tab)510(k)2022-10-14
HeartFlow Analysis
K203329 (opens in new tab)510(k)2021-01-08
HeartFlow Analysis
K190925 (opens in new tab)510(k)2019-08-15
K182035 (opens in new tab)510(k)2018-12-06
Show 3 more
K161772 (opens in new tab)510(k)2016-08-24
K152733 (opens in new tab)510(k)2016-01-13
DEN130045 (opens in new tab)De Novo2014-11-26
FFRct
Peer-reviewed
2 PubMed records name HeartFlow.
- Prognostic value of CT-derived fractional flow reserve for major adverse cardiovascular events in patients with suspected or known coronary artery disease: a systematic review and meta-analysis. (opens in new tab)
- Diagnostic Performance of AI-enabled Plaque Quantification from Coronary CT Angiography Compared with Intravascular Ultrasound. (opens in new tab)
icometrix
FDA decisions
K240712 (opens in new tab)510(k)2024-11-07
icobrain aria
K192962 (opens in new tab)510(k)2020-02-28
icobrain-ctp
K192130 (opens in new tab)510(k)2019-12-13
Icobrain
K181939 (opens in new tab)510(k)2018-11-06
icobrain
K180326 (opens in new tab)510(k)2018-03-08
icobrain
Show 1 more
K161148 (opens in new tab)510(k)2016-08-09
icobrain
Peer-reviewed
5 PubMed records name icometrix.
- Lecanemab in practice: AI-derived MRI predictors of benefit and Amyloid Related Imaging Abnormalities (ARIA). (opens in new tab)
- Uncovering heterogeneous cognitive trajectories in relapsing-remitting multiple sclerosis: a longitudinal study. (opens in new tab)
- Quantifying White Matter Hyperintensities: Automated Volumetry Compared with Visual Grading Scales. (opens in new tab)
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | HeartFlow | icometrix |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Not specified | Not specified |
| Founded | 2007 | 2011 |
| HQ | US | BE |
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Common questions
Open the full radiology comparison
Acute-care triage, mammography screening, CCTA plaque analysis, mobile MRI. 30+ FDA-cleared platforms across stroke, oncology, cardiac. Enterprise sales only — we compared what's deployed where.


