Hologic Genius AI vs Siemens Healthineers AI-Rad Companion
AI-Rad Companion is a set of modules for chest CT nodule measurement, brain MR volumetry, prostate MR lesion work and radiotherapy contouring. Its Pulmonary, Brain MR, Prostate MR and Organs RT modules each carry 510(k)s, the newest for Organs RT in April 2026. A BMC Medicine study of 117 low-dose CT patients found no patient with a nodule missed, at a specificity of 0.708, so about three in ten patients without a nodule were flagged. A US hospital that wants AI chest X-ray reading from Siemens cannot get it, since the vendor's footnote says the Chest X-ray module is not for sale in the U.S. Hologic's Genius AI Detection is a breast tool, a tomosynthesis reader whose cases go to a SecurView 12.0 worklist and which marks about 8 to 10% as most concerning. Siemens delivers its modules through the teamplay platform, with DICOM SR and PACS delivery, so a radiology or radiation oncology department weighing it is committing to teamplay first.
Radiology · Reviewed November 2, 2026

Hologic Genius AI
by Hologic
Genius AI family from Hologic: Genius AI Detection for 3D mammography and Genius Cervical AI for cytology.

Siemens Healthineers AI-Rad Companion
by Siemens Healthineers
AI-Rad Companion: Chest CT, Chest X-ray, Brain MR, Prostate MR and Organs RT (radiotherapy contouring) modules, delivered through teamplay.
When to pick each one
Hologic Genius AI
- Worklist integration with SecurView 12.0
- Priority flag for about 8 to 10% of cases
Siemens Healthineers AI-Rad Companion
- Chest CT, brain MR, prostate MR, RT contouring modules
- Delivered through teamplay with DICOM SR and PACS
Score
Each row shows points earned of points available under the published rubric.
Hologic Genius AI
35of 100
Siemens Healthineers AI-Rad Companion
39of 100
| Dimension | Hologic Genius AI | Siemens Healthineers AI-Rad Companion | Difference |
|---|---|---|---|
| FDA clearance | 18 / 18 | 18 / 18 | 0 |
| HIPAA / SOC2 / BAA | 0 / 10 | 0 / 10 | 0 |
| EHR integrations (count) | 0 / 4.2 | 0 / 4.2 | 0 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 0 / 2.4 | 0 / 2.4 | 0 |
| Peer-reviewed papers | 0 / 18.2 | 0 / 18.2 | 0 |
| RCT / meta-analysis / systematic review | 0 / 7.8 | 0 / 7.8 | 0 |
| Funding & adoption signal | 8.4 / 12 | 12 / 12 | -3.6 |
| Pricing transparency | 2.5 / 5 | 2.5 / 5 | 0 |
| Years in market | 0 / 6 | 0 / 6 | 0 |
Scroll horizontally to see every column.
Pricing
Hologic Genius AI
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| OEM-bundled | n/a | n/a | No public price. Sold with Hologic 3D Mammography systems. |
Siemens Healthineers AI-Rad Companion
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price on the vendor page. |
Evidence
Hologic Genius AI
FDA decisions
K243341 (opens in new tab)510(k)2025-07-31
Genius AI Detection 2.0
DEN210035 (opens in new tab)De Novo2024-01-31
Genius Digital Diagnostics System with Genius Cervical AI algorithm
K230096 (opens in new tab)510(k)2023-05-23
Genius AI Detection 2.0 with CC-MLO Correlation
K221449 (opens in new tab)510(k)2022-10-06
Genius AI Detection 2.0
K201019 (opens in new tab)510(k)2020-11-18
Genius AI Detection
Siemens Healthineers AI-Rad Companion
FDA decisions
K252548 (opens in new tab)510(k)2026-04-10
AI-Rad Companion Organs RT, update
K252608 (opens in new tab)510(k)2025-09-09
AI-Rad Companion Prostate MR, update
K242745 (opens in new tab)510(k)2025-03-27
AI-Rad Companion Organs RT, update
K232899 (opens in new tab)510(k)2024-04-03
AI-Rad Companion Organs RT, update
K222360 (opens in new tab)510(k)2023-04-06
AI-Rad Companion (Cardiovascular), update
Show 8 more
K222361 (opens in new tab)510(k)2022-10-20
AI-Rad Companion (Musculoskeletal)
K213706 (opens in new tab)510(k)2022-04-15
AI-Rad Companion Brain MR, update
K193562 (opens in new tab)510(k)2020-11-06
AI-Rad Companion Organs RT
K193283 (opens in new tab)510(k)2020-07-30
AI-Rad Companion Prostate MR
K193290 (opens in new tab)510(k)2020-06-17
AI-Rad Companion Brain MR
K183268 (opens in new tab)510(k)2019-09-10
AI-Rad Companion (Cardiovascular)
K183271 (opens in new tab)510(k)2019-07-26
AI-Rad Companion (Pulmonary)
K183272 (opens in new tab)510(k)2019-02-01
AI Rad Companion (Engine)
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | Hologic Genius AI | Siemens Healthineers AI-Rad Companion |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Not specified | Not specified |
| Founded | n/a | n/a |
| HQ | US | DE |
Scroll horizontally to see both columns.
Common questions
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