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Adonis vs Amperos

A health system revenue cycle office is the Adonis buyer, going by MedCity's March 2026 customer list: Mount Sinai Health System, Baptist Health South Florida, AdventHealth and ApolloMD. MedCity also reports a $40M Series C (currency not stated) announced March 25, 2026 and led by Quadrille Capital, with total funding above $95M (currency not stated). The vendor says ApolloMD saw a 67% reduction in denials, with no baseline or period given.

Amperos's homepage names Tend, Atlantic Vision Partners, Providence Anesthesiology Associates, Boulder Care, Eyecare Services Partners, Precision Orthopedics and Sports Medicine, Hanger and DOCS Dermatology Group. Its $16M Series A (currency not stated) was announced April 22, 2026 and led by Bessemer Venture Partners.

An eye-care group on ModMed could run either, since both vendors list ModMed, and Adonis's partner page also names athenahealth, Epic, NextGen Healthcare and Canvas. A health system revenue cycle office is Adonis's buyer, and an anesthesiology, orthopedic or ophthalmology group of the kind on Amperos's homepage is Amperos's.

Billing & coding · Reviewed November 2, 2026

Adonis logo

Adonis

by Adonis Technology, Inc. · founded 2022

AI agents that work denials, underpayments and stalled claims for revenue cycle teams.

AM

Amperos

by Amperos Health

Agentic AI that works denied insurance claims through payer portals and recovers provider revenue.

When to pick each one

Adonis

  • Customers named by MedCity include Mount Sinai and AdventHealth
  • Works with Epic, athenahealth, ModMed and NextGen
Read the full Adonis review

Amperos

  • Names Eyecare Services Partners and Atlantic Vision Partners as customers
  • Series A led by Bessemer, announced April 22, 2026
Read the full Amperos review

Score

Each row shows points earned of points available under the published rubric.

Adonis

53of 100

Solid choice

Amperos

41of 100

Competitive
Score by dimension for Adonis and Amperos
DimensionAdonisAmperosDifference
HIPAA / SOC2 / BAA10 / 1010 / 100
EHR integrations (count)9.1 / 18.29.1 / 18.20
Top-3 EHR coverage (Epic / Oracle / Athena)5.6 / 85.6 / 80
Bidirectional write-back0 / 5.20 / 5.20
Peer-reviewed papers0 / 70 / 70
RCT / meta-analysis / systematic review0 / 30 / 30
Funding & adoption signal8.4 / 123 / 12+5.4
Pricing transparency3.3 / 6.53.3 / 6.50
Years in market4.2 / 60 / 6+4.2

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How scores are computed

Pricing

Adonis

TierMonthlyAnnualNotes
Enterprisen/an/aNo public price.

Amperos

TierMonthlyAnnualNotes
Enterprisen/an/aNo public price.

Compliance and integrations

Documented from each vendor’s own pages.

SpecAdonisAmperos
Free tierNo / unverifiedNo / unverified
HIPAAYesYes
SOC 2 Type IIYesYes
EHR integrationsEpic, athenahealth, AdvancedMD, ModMed, NextGen Healthcare, CanvaseClinicalWorks, athenahealth, NextGen, Epic, ModMed, Dentrix
Founded2022n/a
HQUSUS

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Common questions

Open the full billing & coding comparison

Autonomous coding (CodaMetrix #1 KLAS 2026), denial prevention, prior-auth automation. The single fastest path to ROI in healthcare AI is RCM — these tools deliver it.