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Adonis vs Waystar

Adonis agents research denials and prepare appeals, per the vendor, and Waystar lists denial recovery inside a wider platform that also covers eligibility, estimates, authorizations, remittance and patient payments. For a specialty group on athenahealth, ModMed or NextGen with a denials backlog, Adonis names those EHRs on its partner list while Waystar's homepage names none, which makes Waystar the weaker fit. Adonis customers named by MedCity include Mount Sinai, Baptist Health South Florida, AdventHealth and ApolloMD. The vendor reports a 67% denial reduction at ApolloMD, with no baseline or period. Waystar suits a health system billing office that wants front-end clearance and patient payments on the same platform as its denial recovery. It has traded on Nasdaq (WAY) since June 2024 and says it covers 1M+ providers. Adonis, with $40M raised in a March 2026 Series C, is the vendor to weigh when the problem is claims already stalled with a payer.

Billing & coding · Reviewed November 2, 2026

Adonis logo

Adonis

by Adonis Technology, Inc. · founded 2022

AI agents that work denials, underpayments and stalled claims for revenue cycle teams.

Waystar logo

Waystar

by Waystar

AI-powered healthcare payments platform for revenue cycle: eligibility, authorizations, claims, denials and patient payments (AltitudeAI).

When to pick each one

Adonis

  • Epic, athenahealth, ModMed and NextGen on partner list
  • AI agents for denials and appeals, vendor-stated
  • MedCity names Mount Sinai and AdventHealth as customers
Read the full Adonis review

Waystar

  • Nasdaq-listed since June 2024
  • Eligibility through patient payments on one platform
  • Vendor says it reaches 1M+ providers
Read the full Waystar review

Score

Each row shows points earned of points available under the published rubric.

Adonis

53of 100

Solid choice

Waystar

33of 100

Competitive
Score by dimension for Adonis and Waystar
DimensionAdonisWaystarDifference
HIPAA / SOC2 / BAA10 / 1010 / 100
EHR integrations (count)9.1 / 18.20 / 18.2+9.1
Top-3 EHR coverage (Epic / Oracle / Athena)5.6 / 80 / 8+5.6
Bidirectional write-back0 / 5.20 / 5.20
Peer-reviewed papers0 / 70 / 70
RCT / meta-analysis / systematic review0 / 30 / 30
Funding & adoption signal8.4 / 1212 / 12-3.6
Pricing transparency3.3 / 6.53.3 / 6.50
Years in market4.2 / 60 / 6+4.2

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How scores are computed

Pricing

Adonis

TierMonthlyAnnualNotes
Enterprisen/an/aNo public price.

Waystar

TierMonthlyAnnualNotes
Enterprisen/an/aNo public price. Enterprise contracts.

Compliance and integrations

Documented from each vendor’s own pages.

SpecAdonisWaystar
Free tierNo / unverifiedNo / unverified
HIPAAYesYes
SOC 2 Type IIYesYes
EHR integrationsEpic, athenahealth, AdvancedMD, ModMed, NextGen Healthcare, CanvasNot specified
Founded2022n/a
HQUSUS

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Common questions

Open the full billing & coding comparison

Autonomous coding (CodaMetrix #1 KLAS 2026), denial prevention, prior-auth automation. The single fastest path to ROI in healthcare AI is RCM — these tools deliver it.