Amperos vs Ember
Amperos announced its Series A on April 22, 2026, led by Bessemer Venture Partners. The vendor reports 5.3x ROI and 56% lower cost to collect for Boulder Care, and its pages describe work on claims a payer has already denied.
The vendor says Ember reviews encounters before claims go out. Its Coding Engine checks 100% of encounters against national standards, payer policies and contracts, with a rule citation on every flag, and its Appeal Engine drafts letters from CARC and RARC codes. The homepage states SOC 2 Type II, HITRUST e1 and HIPAA, and names Availity and Waystar. HIT Consultant reported a US$4.3M seed on November 19, 2025.
A specialty practice whose denials start at coding gets more from Ember, so Amperos is the weaker pick there. A DME supplier with a pile of denied claims is Amperos's buyer. An Oracle Health hospital system shopping for review ahead of submission is Ember's, and the vendor says six health systems are live on Oracle Health.
Billing & coding · Reviewed November 2, 2026
When to pick each one
Amperos
- Series A led by Bessemer, April 22, 2026
- Vendor reports 5.3x ROI at Boulder Care
Ember
- Reviews encounters before claims are submitted
- SOC 2 Type II and HITRUST e1 on homepage
- Oracle Health live at six systems, vendor says
Score
Each row shows points earned of points available under the published rubric.
Amperos
41of 100
Ember
56of 100
| Dimension | Amperos | Ember | Difference |
|---|---|---|---|
| HIPAA / SOC2 / BAA | 10 / 10 | 10 / 10 | 0 |
| EHR integrations (count) | 9.1 / 18.2 | 18.2 / 18.2 | -9.1 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 5.6 / 8 | 8 / 8 | -2.4 |
| Bidirectional write-back | 0 / 5.2 | 0 / 5.2 | 0 |
| Peer-reviewed papers | 0 / 7 | 0 / 7 | 0 |
| RCT / meta-analysis / systematic review | 0 / 3 | 0 / 3 | 0 |
| Funding & adoption signal | 3 / 12 | 3 / 12 | 0 |
| Pricing transparency | 3.3 / 6.5 | 3.3 / 6.5 | 0 |
| Years in market | 0 / 6 | 0 / 6 | 0 |
Scroll horizontally to see every column.
Pricing
Amperos
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. |
Ember
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. |
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | Amperos | Ember |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | eClinicalWorks, athenahealth, NextGen, Epic, ModMed, Dentrix | athenahealth, ModMed, eClinicalWorks, Nextech, Veradigm, NextGen Healthcare, Greenway Health, Epic, Oracle Health, HST Pathways, Surgical Information Systems, MediReport, AdvancedMD, DrChrono, Altera |
| Founded | n/a | n/a |
| HQ | US | US |
Scroll horizontally to see both columns.
Common questions
Open the full billing & coding comparison
Autonomous coding (CodaMetrix #1 KLAS 2026), denial prevention, prior-auth automation. The single fastest path to ROI in healthcare AI is RCM — these tools deliver it.

