MedAI Verdict
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Harrison.ai vs Pearl

Harrison.ai, the company behind Annalise, sells chest X-ray, head CT and chest CT reading to hospitals, emergency departments and teleradiology services. NHS Grampian figures in a Scottish Health Technologies Group summary give sensitivity of 78%, specificity of 91%, positive predictive value of 3% and negative predictive value of 99.99%. A Radiology study of 5,235 patients found Annalise Enterprise CXR v3.8 and six other devices all produced more false positives than radiologist reports. Annalise shows nine openFDA decisions, from CXR Triage Pneumothorax in February 2022 to Annalise Enterprise in March 2026 (applicant Harrison-AI Medical Pty, Ltd.), while press coverage says twelve.

Pearl reads dental radiographs, and a hospital radiology department and a dental practice do not buy the same product. Second Opinion has eight openFDA decisions, from March 2022 to November 2025, and marks up to 18 findings per image on bitewing, periapical and panoramic films. Pearl is for a dental support organization standardizing reads across offices. Annalise is for an emergency department with chest films and head CTs.

Radiology · Reviewed November 2, 2026

Harrison.ai logo

Harrison.ai

by Harrison.ai

Imaging AI for chest X-ray, head CT and chest CT, with up to 130 findings on head CT (vendor figure).

Pearl logo

Pearl

by Pearl Inc. · founded 2019

FDA-cleared dental x-ray AI (Second Opinion) that marks caries, bone loss and restorations, for dentists and DSOs.

When to pick each one

Harrison.ai

  • Chest X-ray, head CT and chest CT reading
  • Nine openFDA decisions, press says twelve
  • Returns DICOM Secondary Capture to PACS
Read the full Harrison.ai review

Pearl

  • Dental bitewing, periapical and panoramic radiographs
  • Eight openFDA decisions, March 2022 to November 2025
Read the full Pearl review

Score

Each row shows points earned of points available under the published rubric.

Harrison.ai

35of 100

Competitive

Pearl

33of 100

Competitive
Score by dimension for Harrison.ai and Pearl
DimensionHarrison.aiPearlDifference
FDA clearance18 / 1818 / 180
HIPAA / SOC2 / BAA0 / 100 / 100
EHR integrations (count)0 / 4.20 / 4.20
Top-3 EHR coverage (Epic / Oracle / Athena)0 / 2.40 / 2.40
Peer-reviewed papers0 / 18.20 / 18.20
RCT / meta-analysis / systematic review0 / 7.80 / 7.80
Funding & adoption signal8.4 / 123 / 12+5.4
Pricing transparency2.5 / 52.5 / 50
Years in market0 / 64.2 / 6-4.2

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How scores are computed

Pricing

Harrison.ai

TierMonthlyAnnualNotes
Enterprisen/an/aNo public price. Book a demo.

Pearl

TierMonthlyAnnualNotes
Enterprisen/an/aNo public price.

Evidence

Harrison.ai

FDA decisions

Show 4 more

Pearl

FDA decisions

Show 3 more

Compliance and integrations

Documented from each vendor’s own pages.

SpecHarrison.aiPearl
Free tierNo / unverifiedNo / unverified
HIPAANo / unverifiedNo / unverified
SOC 2 Type IINo / unverifiedNo / unverified
EHR integrationsNot specifiedNot specified
Foundedn/a2019
HQAUUS

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Common questions

Open the full radiology comparison

Acute-care triage, mammography screening, CCTA plaque analysis, mobile MRI. 30+ FDA-cleared platforms across stroke, oncology, cardiac. Enterprise sales only — we compared what's deployed where.