Elucid vs Hologic Genius AI
Elucid's PlaqueIQ quantifies coronary plaque from CT angiograms, including non-calcified plaque and lipid-rich necrotic core according to Elucid's 2024 release, and the analysis has carried a Category I CPT code, 75577, since January 2026. A cardiology group that wants plaque composition in its coronary CT reports sends the images to Elucid. Hologic's Genius AI Detection runs integrated on Hologic's own mammography systems, listed as 3Dimensions and Selenia Dimensions, and the 510(k) K243341, decided in July 2025, also names Envision. It marks lesions on each tomosynthesis slice, gives a case score, and its Reading Priority Indicator flags the 8 to 10 percent of cases that look most concerning. SecurView 12.0 carries the worklist integration. A screening center on those Hologic units gets all of that with the system, and the vendor cites 94% sensitivity from FDA documents.
Radiology · Reviewed November 2, 2026

Elucid
by Elucid Bioimaging
PlaqueIQ analyzes coronary plaque on CT angiograms, with FDA 510(k) clearances in September 2024 and September 2026.

Hologic Genius AI
by Hologic
Genius AI family from Hologic: Genius AI Detection for 3D mammography and Genius Cervical AI for cytology.
When to pick each one
Elucid
- Quantifies non-calcified plaque on coronary CT angiograms
- Category I CPT code from January 2026
Hologic Genius AI
- Genius AI Detection integrated on Hologic mammography systems
- SecurView 12.0 worklist integration
- Reading Priority Indicator flags 8 to 10% of cases
Score
Each row shows points earned of points available under the published rubric.
Elucid
43of 100
Hologic Genius AI
35of 100
| Dimension | Elucid | Hologic Genius AI | Difference |
|---|---|---|---|
| FDA clearance | 18 / 18 | 18 / 18 | 0 |
| HIPAA / SOC2 / BAA | 0 / 10 | 0 / 10 | 0 |
| EHR integrations (count) | 0 / 4.2 | 0 / 4.2 | 0 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 0 / 2.4 | 0 / 2.4 | 0 |
| Peer-reviewed papers | 12.7 / 18.2 | 0 / 18.2 | +12.7 |
| RCT / meta-analysis / systematic review | 0 / 7.8 | 0 / 7.8 | 0 |
| Funding & adoption signal | 3 / 12 | 8.4 / 12 | -5.4 |
| Pricing transparency | 2.5 / 5 | 2.5 / 5 | 0 |
| Years in market | 0 / 6 | 0 / 6 | 0 |
Scroll horizontally to see every column.
Pricing
Elucid
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Per analysis | n/a | n/a | No public price. Providers are billed per analysis. Category I CPT code 75577 has applied since January 1, 2026. |
Hologic Genius AI
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| OEM-bundled | n/a | n/a | No public price. Sold with Hologic 3D Mammography systems. |
Evidence
Elucid
FDA decisions
K261855 (opens in new tab)510(k)2026-09-18
Elucid PlaqueIQ
K241524 (opens in new tab)510(k)2024-09-12
Elucid PlaqueIQ
Peer-reviewed
2 PubMed records name Elucid.
Hologic Genius AI
FDA decisions
K243341 (opens in new tab)510(k)2025-07-31
Genius AI Detection 2.0
DEN210035 (opens in new tab)De Novo2024-01-31
Genius Digital Diagnostics System with Genius Cervical AI algorithm
K230096 (opens in new tab)510(k)2023-05-23
Genius AI Detection 2.0 with CC-MLO Correlation
K221449 (opens in new tab)510(k)2022-10-06
Genius AI Detection 2.0
K201019 (opens in new tab)510(k)2020-11-18
Genius AI Detection
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | Elucid | Hologic Genius AI |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Not specified | Not specified |
| Founded | n/a | n/a |
| HQ | n/a | US |
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Common questions
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Acute-care triage, mammography screening, CCTA plaque analysis, mobile MRI. 30+ FDA-cleared platforms across stroke, oncology, cardiac. Enterprise sales only — we compared what's deployed where.
