HeartFlow vs Overjet
Twelve openFDA records sit under Overjet, Inc. since 2021, the latest K261059 (multi-image caries and charting), decided August 6, 2026, covering bitewing and periapical radiographs and CBCT. Overjet's Trust Center page states a completed HITRUST audit, and its release put the March 2024 Series C at $53.2M, led by March Capital. Two studies report Caries Assist accuracy with different designs. A 2025 Frontiers in Dental Medicine accuracy study reported dentin sensitivity of 0.91, and a 2026 Journal of Dentistry study comparing bitewing, ICDAS and Caries Assist against micro-CT reported AI sensitivity of 56% at the dentin threshold. HeartFlow's homepage lists FFRct, plaque and Roadmap analyses on coronary CT, and its 10-K shows 2025 revenue of $176.0M for a Nasdaq company (HTFL). Their audiences are separate, since Overjet sells to dentists and DSOs and HeartFlow's homepage addresses cardiac imaging.
Radiology · Reviewed November 2, 2026
HeartFlow
by HeartFlow · founded 2007
Coronary CT angiogram analysis: CT-derived fractional flow reserve (FFRct), plaque analysis and a CCTA reading aid.
Overjet
by Overjet · founded 2018
FDA-cleared dental x-ray AI for caries, calculus, periapical lesions and tooth charting, for dentists and dental groups.
When to pick each one
HeartFlow
- Coronary CT analysis for cardiac imaging units
- Cloud-processed FFRct from a coronary CT angiogram
Overjet
- Dental x-ray AI with twelve openFDA records since 2021
- HITRUST audit stated on Trust Center page
Score
Each row shows points earned of points available under the published rubric.
HeartFlow
66of 100
Overjet
42of 100
| Dimension | HeartFlow | Overjet | Difference |
|---|---|---|---|
| FDA clearance | 18 / 18 | 18 / 18 | 0 |
| HIPAA / SOC2 / BAA | 0 / 10 | 0 / 10 | 0 |
| EHR integrations (count) | 0 / 4.2 | 0 / 4.2 | 0 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 0 / 2.4 | 0 / 2.4 | 0 |
| Peer-reviewed papers | 12.7 / 18.2 | 0 / 18.2 | +12.7 |
| RCT / meta-analysis / systematic review | 7.8 / 7.8 | 0 / 7.8 | +7.8 |
| Funding & adoption signal | 8.4 / 12 | 8.4 / 12 | 0 |
| Pricing transparency | 2.5 / 5 | 2.5 / 5 | 0 |
| Years in market | 6 / 6 | 6 / 6 | 0 |
Scroll horizontally to see every column.
Pricing
HeartFlow
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Per study | n/a | n/a | No public list price. The 10-K describes revenue as pay-per-use. |
Overjet
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. |
Evidence
HeartFlow
FDA decisions
K250902 (opens in new tab)510(k)2025-07-18
HeartFlow Analysis
K213857 (opens in new tab)510(k)2022-10-14
HeartFlow Analysis
K203329 (opens in new tab)510(k)2021-01-08
HeartFlow Analysis
K190925 (opens in new tab)510(k)2019-08-15
K182035 (opens in new tab)510(k)2018-12-06
Show 3 more
K161772 (opens in new tab)510(k)2016-08-24
K152733 (opens in new tab)510(k)2016-01-13
DEN130045 (opens in new tab)De Novo2014-11-26
FFRct
Peer-reviewed
2 PubMed records name HeartFlow.
- Prognostic value of CT-derived fractional flow reserve for major adverse cardiovascular events in patients with suspected or known coronary artery disease: a systematic review and meta-analysis. (opens in new tab)
- Diagnostic Performance of AI-enabled Plaque Quantification from Coronary CT Angiography Compared with Intravascular Ultrasound. (opens in new tab)
Overjet
FDA decisions
K261059 (opens in new tab)510(k)2026-08-06
Overjet Multi-Image Caries and Charting Assist
K251514 (opens in new tab)510(k)2025-12-05
Overjet CBCT Assist
K241681 (opens in new tab)510(k)2024-09-09
Overjet Image Enhancement Assist
K241684 (opens in new tab)510(k)2024-08-27
Overjet Charting Assist (updated)
K233738 (opens in new tab)510(k)2024-03-04
Overjet Caries Assist-Pediatric
Show 6 more
K233590 (opens in new tab)510(k)2024-02-23
Overjet Charting Assist
K231678 (opens in new tab)510(k)2023-09-21
Overjet Periapical Radiolucency Assist
K222746 (opens in new tab)510(k)2023-03-27
Overjet Caries Assist
K220928 (opens in new tab)510(k)2022-12-16
Overjet Calculus Assist
K212519 (opens in new tab)510(k)2022-05-10
Overjet Caries Assist
K210187 (opens in new tab)510(k)2021-05-19
Overjet Dental Assist
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | HeartFlow | Overjet |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Not specified | Not specified |
| Founded | 2007 | 2018 |
| HQ | US | US |
Scroll horizontally to see both columns.
Common questions
Open the full radiology comparison
Acute-care triage, mammography screening, CCTA plaque analysis, mobile MRI. 30+ FDA-cleared platforms across stroke, oncology, cardiac. Enterprise sales only — we compared what's deployed where.