Pearl vs Ultromics EchoGo
Ultromics belongs in an echo lab. EchoGo Heart Failure flags findings suggestive of HFpEF from a single apical four-chamber clip in adults over 25 with an ejection fraction of 50% or more, and the vendor cites 90.3% sensitivity and 86.1% specificity, sourced to clearance K240013. EchoGo Amyloidosis screens adults 65 and older with heart failure. Cardiology groups and hospital echo services buy it, and the vendor lists CPT Category III code 0932T for the heart failure tool.
Pearl's Second Opinion goes to a dental practice reading intraoral and panoramic films. The openFDA record for Pearl holds eight Second Opinion decisions, the latest a panoramic tool from November 2025, while the vendor's home page claims 26 or more clearances. Pearl's news page names Smile Brands and ClearDent Canada, and Ultromics names City of Hope, University Hospitals and UChicago Medicine as sites, so the customers come from separate fields.
Radiology · Reviewed November 2, 2026

Pearl
by Pearl Inc. · founded 2019
FDA-cleared dental x-ray AI (Second Opinion) that marks caries, bone loss and restorations, for dentists and DSOs.

Ultromics EchoGo
by Ultromics
FDA-cleared AI on echocardiograms that flags heart failure with preserved ejection fraction and screens for cardiac amyloidosis.
When to pick each one
Pearl
- Eight Second Opinion decisions on openFDA
- Panoramic caries cleared November 2025
- Bone level measurement cleared May 2025
Ultromics EchoGo
- HFpEF flag from one apical four-chamber clip
- Vendor lists CPT Category III 0932T
- Trust Center lists HIPAA and ISO/IEC 27001
Score
Each row shows points earned of points available under the published rubric.
Pearl
33of 100
Ultromics EchoGo
42of 100
| Dimension | Pearl | Ultromics EchoGo | Difference |
|---|---|---|---|
| FDA clearance | 18 / 18 | 18 / 18 | 0 |
| HIPAA / SOC2 / BAA | 0 / 10 | 6 / 10 | -6 |
| EHR integrations (count) | 0 / 4.2 | 0 / 4.2 | 0 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 0 / 2.4 | 0 / 2.4 | 0 |
| Peer-reviewed papers | 0 / 18.2 | 0 / 18.2 | 0 |
| RCT / meta-analysis / systematic review | 0 / 7.8 | 0 / 7.8 | 0 |
| Funding & adoption signal | 3 / 12 | 8.4 / 12 | -5.4 |
| Pricing transparency | 2.5 / 5 | 2.5 / 5 | 0 |
| Years in market | 4.2 / 6 | 0 / 6 | +4.2 |
Scroll horizontally to see every column.
Pricing
Pearl
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. |
Ultromics EchoGo
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. |
Evidence
Pearl
FDA decisions
K250525 (opens in new tab)510(k)2025-11-14
Second Opinion Panoramic
K243234 (opens in new tab)510(k)2025-06-12
Second Opinion CS
K243989 (opens in new tab)510(k)2025-05-23
Second Opinion 3D
K243230 (opens in new tab)510(k)2025-05-09
Second Opinion BLE
K243893 (opens in new tab)510(k)2025-05-05
Second Opinion Pediatric
Show 3 more
K242600 (opens in new tab)510(k)2025-04-11
Second Opinion Periapical Radiolucency Contours
K242522 (opens in new tab)510(k)2025-01-16
Second Opinion CC
K210365 (opens in new tab)510(k)2022-03-04
Second Opinion
Ultromics EchoGo
FDA decisions
K240860 (opens in new tab)510(k)2024-11-15
EchoGo Amyloidosis (1.0)
K240013 (opens in new tab)510(k)2024-09-23
EchoGo Heart Failure (2.0)
K222463 (opens in new tab)510(k)2022-11-23
EchoGo Heart Failure 1.0
K213275 (opens in new tab)510(k)2021-12-20
EchoGo Core (2.0)
K201555 (opens in new tab)510(k)2020-12-18
EchoGo Pro v1.0.2
Show 1 more
K191171 (opens in new tab)510(k)2019-11-13
EchoGo Core
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | Pearl | Ultromics EchoGo |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Not specified | Not specified |
| Founded | 2019 | n/a |
| HQ | US | GB |
Scroll horizontally to see both columns.
Common questions
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Acute-care triage, mammography screening, CCTA plaque analysis, mobile MRI. 30+ FDA-cleared platforms across stroke, oncology, cardiac. Enterprise sales only — we compared what's deployed where.
