Limbic

At a glance

Pricing

Enterprise (NHS, IAPT services).

HIPAA

Not disclosed

SOC 2

Not disclosed

EHRs

—

Founded

—

HQ

UK

Bottom line

NHS-deployed AI for self-referral triage + therapist assistant.

Free tier available.

Overview

Pricing

What it costs

Free tier only; no paid plans publicly disclosed.

Source: vendor pricing page. Verified May 23, 2026.

Compliance + integration

What deploys cleanly

Carries NHS DTAC per vendor documentation. Independent attestation review is the buyer's responsibility before clinical deployment.

Peer-reviewed coverage

What the literature says

5 peer-reviewed studies indexed on PubMed evaluate Limbic in clinical contexts. The most relevant are shown below, ranked by editorial relevance score combining title match, study design, recency, and journal tier.

Molecular signatures and biomarker development for limbic-predominant age-related TDP-43 encephalopathy (LATE).

Wu L, Akingbade T, Nelson PT, et al.· Acta Neuropathol· 2026

Limbic-predominant age-related TDP-43 encephalopathy (LATE) is a neurodegenerative disease marked by TDP-43 proteinopathy, affecting approximately one-third of individuals aged 80 and above. LATE neuropathological change (LATE-NC) is characterized by the accumulation of phosphorylated TDP-43 preferentially in the limbic system, with potential extension to the neocortex and other brain regions. Notably, the anatomic pattern of LATE-NC differs from that seen in frontotemporal lobar degeneration with TDP-43-immunoreactive inclusions (FTLD-TDP).  LATE-NC can occur in a "p…

Regional and network-level convergent structural effects of electroconvulsive therapy in depression: a neuroimaging meta-analysis.

Meng H, Yang Y, Cui Q, et al.· J Psychiatr Res· 2026Meta-Analysis

Neuroimaging studies have suggested macroscale effects of electroconvulsive therapy (ECT) on brain structures in depression, but findings remain inconsistent. The current study aims to investigate whether ECT exhibits convergence in the treatment effect at the regional and network levels and to explore the relationship between ECT-related structural effect and neurotransmitter systems. We conducted a comprehensive search in PubMed and Web of Science, identifying eleven studies on ECT effects related to whole-brain gray matter volume (GMV) in depression. A coordinate-based meta-analysis named…

Tinnitus.

Vanneste S, De Ridder D, Gallus S, et al.· Nat Rev Dis Primers· 2026

Tinnitus is the perception of sound without a corresponding external sound source. This condition affects approximately 14% of adults, with approximately 2% experiencing severe symptoms. Underlying mechanisms of tinnitus suggest involvement of both peripheral and central processes, in which cochlear injury and deafferentation may trigger maladaptive plasticity, increased central gain, and thalamocortical dysrhythmia, modulated by limbic and salience networks. Neuroinflammation, somatosensory-auditory coupling and other factors, such as stress, may contribute to chronicity. Clinical expression…

Uncovering distinct spatiotemporal trajectories of T-N mismatch subtypes with likely co-pathology in Alzheimer's disease using event-based modeling.

Lyu X, Brown CA, Duong MT, et al.· Alzheimers Dement· 2026

In Alzheimer's disease (AD), tau-neurodegeneration (T-N) mismatch has been proposed to reflect non-AD processes such as transactive response DNA binding protein 43 kDa and vascular disease. We aimed to characterize the spatiotemporal trajectories of T-N mismatch that may reflect non-AD progression. We performed T-N regression on 710 Alzheimer's Disease Neuroimaging Initiative participants using cortical thickness and 18F-flortaucipir uptake across 20 cortical regions. SuStaIn, a data-driven phenotype discovery and staging algorithm, was applied to standardized T-N residuals in canonical…

Neural correlates of Parkinson's improvements after combined digital-levodopa therapy: a pilot study.

Catalogna M, Saporta N, Tamir T, et al.· Brain Commun· 2026

Parkinson's disease is characterized by progressive degeneration of dopaminergic neurons within the nigrostriatal pathway, leading to motor and non-motor deficits that become less responsive to chronic dopaminergic pharmacotherapy. Here, we examined whether a multimodal mobile digital intervention, DopApp™, delivering adaptive daily training across sensorimotor, psychological and rehabilitation domains, can induce functional reorganization of thalamocortical motor and limbic networks and augment dopaminergic treatment effects in Parkinson's disease. To test this hypothesis, we conducte…

See all on PubMed