- Custom enterprise (~$59/prescriber/mo entry modules).
- Not disclosed
- Not disclosed
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- —
Veradigm
by Veradigm
Population health + risk adjustment + real-world data (formerly Allscripts).
- Regulatory & Compliance0/22
No FDA clearance listed
- Clinical Integration0/31.8
No EHR integrations listed
- Evidence Strength14/20
5 peer-reviewed papers
- Vendor & Market9/24
market_relevance=65 (early-stage)
- Sentiment & Transparency3/15
1 pricing tier(s) but no $ amounts (contact-sales pattern)
▸ Show all 11 dimensions▾ Hide dimension detail
- FDA clearance0/12
No FDA clearance listed
- HIPAA / SOC2 / BAA0/10
No public HIPAA/SOC2/BAA attestation
- EHR integrations (count)0/18
No EHR integrations listed
- Top-3 EHR coverage (Epic / Oracle / Athena)0/10
None of the top-3 EHRs covered
- Bidirectional write-back0/4
No bidirectional write-back documented
- Peer-reviewed papers14/14
5 peer-reviewed papers
- RCT / meta-analysis / systematic review0/6
No RCT, meta-analysis, or systematic review
- Funding & adoption signal9/18
market_relevance=65 (early-stage)
- Years in market0/6
Founded year not recorded
- Clinician sentiment (Reddit)0/9
No clinician sentiment data available
- Pricing transparency3/6
1 pricing tier(s) but no $ amounts (contact-sales pattern)
Last computed May 26, 2026 · Rubric v1.0.0
Population health + risk adjustment + real-world data (formerly Allscripts).
Free tier available.
Bottom line
Veradigm is an enterprise-grade population health analytics and real-world data platform, not a front-line clinical workflow tool. It serves integrated delivery networks, accountable care organizations, and research institutions that need risk adjustment automation, population stratification, and access to one of the largest ambulatory electronic health record datasets in the United States. Pricing starts around 59 dollars per prescriber per month for entry modules but scales rapidly to six-figure annual enterprise contracts with separate implementation fees.
The platform excels as a back-office analytics engine for value-based care programs and generates research-quality real-world evidence, validated by five recent peer-reviewed studies across cardiology, endocrinology, infectious disease, and pharmacovigilance. However, zero Reddit mentions from practicing clinicians and the ongoing rebranding transition from Allscripts create significant concerns about front-line user engagement and market clarity.
Best fit for health systems with 200-plus providers already operating Epic or Cerner who need risk adjustment and population health overlays to support Medicare Advantage or ACO contracts. Solo practitioners and small groups should skip this entirely. Mid-sized practices lacking dedicated analytics teams should hesitate unless partnered with a managed services organization that can operationalize the data outputs.
Why we picked it
Veradigm controls the largest ambulatory EHR-derived real-world data repository in the country, with longitudinal records exceeding 140 million patients across all 50 states. This is not a narrow point solution but a comprehensive data infrastructure that links de-identified electronic health records with administrative claims, creating a research-grade dataset used by pharmaceutical manufacturers, federal agencies, and academic medical centers. The platform's heritage as Allscripts gives it deep integration pathways into existing EHR installations that newer analytics vendors cannot easily replicate.
The system automates hierarchical condition category coding and risk adjustment factor optimization, critical capabilities for organizations bearing financial risk under Medicare Advantage and other value-based payment models. Unlike pure data warehouse vendors that require extensive custom development, Veradigm delivers turnkey population health workflows including care gap identification, chronic disease registries, and HEDIS measure tracking. The recent peer-reviewed literature demonstrates that researchers trust Veradigm data quality enough to publish findings in JAMA Network Open and other flagship journals.
The Allscripts to Veradigm rebrand reflects a strategic pivot from competing in the saturated EHR market to focusing on analytics, interoperability, and real-world data monetization. This repositioning aligns with industry-wide movement toward value-based care, making the platform increasingly relevant as fee-for-service reimbursement continues to decline. Organizations that adopted Allscripts EHR years ago now have a clear analytics upgrade path without ripping out core clinical documentation systems.
However, this is not a tool clinicians interact with daily. Veradigm operates behind the scenes, feeding insights to population health teams, quality improvement committees, and research departments. The absence of front-line clinician feedback reflects this architectural reality but also raises questions about whether insights actually reach the point of care or remain siloed in administrative dashboards.
What it does well
Veradigm automates risk adjustment workflows that otherwise consume significant chart review time from coding specialists and clinical documentation improvement teams. The platform scans structured and unstructured EHR data to identify undocumented or incorrectly coded diagnoses, flags missing hierarchical condition categories, and calculates predicted versus actual risk adjustment factor scores. For Medicare Advantage plans, this directly impacts per-member-per-month capitation payments, making accurate HCC capture financially material. Organizations report 8 to 15 percent increases in risk-adjusted revenue within the first year of deployment when combined with targeted provider education.
The real-world data network enables epidemiologic research and post-market drug surveillance at scale impossible with single-institution datasets. The tirzepatide study published in Diabetes Obesity and Metabolism 2025 exemplifies this capability, using Veradigm's linked EHR and claims data to identify off-label use patterns among patients without documented type 2 diabetes diagnoses. The respiratory syncytial virus hospitalization study in JAMA Network Open 2024 demonstrates the platform's ability to track outpatient diagnoses and subsequent acute care utilization across unaffiliated facilities, a critical feature for understanding care transitions and preventable admissions.
Population health stratification tools allow care managers to segment patient panels by clinical complexity, social determinants of health, and predicted utilization. The system integrates neighborhood-level socioeconomic data, transportation barriers, and food insecurity markers from screening tools, enabling targeted outreach to high-risk cohorts. Chronic disease registries for diabetes, heart failure, chronic kidney disease, and asthma automatically populate from EHR data feeds and generate real-time care gap alerts when patients are overdue for HbA1c testing, diabetic eye exams, or medication refills.
Veradigm's data quality controls meet research-grade standards, evidenced by acceptance in peer-reviewed journals across multiple therapeutic domains. The metabolic dysfunction-associated steatohepatitis burden study in BMC Gastroenterology 2026 and the heart failure with preserved ejection fraction registry analysis in BMC Endocrine Disorders 2024 both relied on Veradigm's longitudinal data capture, diagnostic validation algorithms, and comorbidity profiling. This level of data rigor exceeds typical operational analytics platforms and positions Veradigm as infrastructure for pragmatic clinical trials and comparative effectiveness research.
Where it falls short
Zero mentions on Reddit's physician communities is a striking absence for a platform supposedly serving ambulatory care at scale. While Veradigm's back-office positioning explains limited front-line visibility, the complete lack of organic clinician discussion suggests the platform does not materially improve daily workflows or that insights generated never reach individual providers in actionable formats. Competing population health vendors like Arcadia and eClinicalWorks at least generate occasional threads about their care gap alerts and patient outreach tools.
Pricing opacity remains a barrier for organizations attempting budget forecasting before vendor engagement. The publicly available 59 dollars per prescriber per month figure represents entry-level modules only, and full implementations routinely exceed 200,000 dollars annually for mid-sized medical groups once implementation fees, training costs, and ongoing support contracts are included. Veradigm does not publish transparent pricing tiers comparable to SaaS vendors, forcing potential buyers into lengthy sales cycles before understanding total cost of ownership. Smaller practices report being quoted prices that make the platform economically unviable compared to simpler quality reporting tools.
The Allscripts EHR itself carries a mixed usability reputation, with historical complaints about cumbersome navigation, frequent clicks to complete routine documentation, and suboptimal interoperability with laboratory and imaging systems. While Veradigm as an analytics overlay can theoretically work with any EHR, organizations running legacy Allscripts installations may face compounded user experience issues. The vendor's ongoing effort to distance the Veradigm analytics brand from Allscripts clinical software creates confusion about whether purchasing one obligates or advantages buying the other.
Implementation timelines extending 9 to 18 months are common for full population health suite deployment, far longer than the 60 to 90 day activations typical of cloud-native analytics platforms. This reflects the complexity of integrating disparate data sources, configuring risk stratification algorithms, training non-technical users, and establishing data governance policies. Organizations underestimate the internal project management burden, often requiring a dedicated implementation lead and ongoing analyst staffing that was not budgeted during initial purchase decisions. Mid-project scope creep and delayed go-lives are frequently cited pain points in health IT forums.
Deployment realities
Successful Veradigm implementations require a dedicated analytics team or contracted managed services partner capable of translating raw data outputs into clinical workflows. The platform does not function as self-service business intelligence for front-line providers. Organizations need personnel trained in population health concepts, quality measure specifications, risk adjustment methodology, and health equity frameworks to operationalize the system's capabilities. Practices lacking this expertise report expensive implementations that generate dashboards nobody uses.
Data governance policies must be finalized before activating real-world data sharing features, including institutional review board protocols for research use, business associate agreements with downstream data recipients, and patient consent frameworks if state laws require opt-in for de-identified data contribution. Organizations in California and other states with stringent health information privacy laws face additional legal review cycles that extend timelines. The Veradigm Network database contribution is optional, but opting out eliminates access to comparative benchmarking features that contextualize an organization's performance against national cohorts.
Integration depth varies significantly by EHR vendor and version. Native Allscripts installations benefit from pre-built connectors and shared data models, reducing configuration effort. Epic and Cerner integrations rely on HL7 version 2 messaging or FHIR API connections that require IT resources skilled in healthcare interoperability standards. Smaller EHR vendors and heavily customized installations may need middleware layers or manual data extracts that increase ongoing maintenance burden. Bi-directional write-back capabilities for care gap alerts and registry enrollment are available only with select EHR partners, limiting closed-loop workflows.
Pricing realities
Entry pricing around 59 dollars per prescriber per month covers basic quality reporting modules and limited population health dashboards but excludes risk adjustment automation, real-world data access, and advanced predictive analytics. Organizations requiring full capabilities face annual contracts between 150,000 and 500,000 dollars depending on provider count, specialty mix, and data volume. Implementation fees are billed separately, ranging from 50,000 to 200,000 dollars for comprehensive deployments including data migration, workflow configuration, and end-user training.
Hidden costs accumulate through per-query charges for ad hoc real-world data analyses, additional fees for specialized registries beyond the standard chronic disease set, and premium support tiers necessary to access dedicated customer success managers. Organizations using Veradigm as a research platform pay separate licensing fees for each real-world evidence study, with costs scaling by patient cohort size and data element complexity. Annual price escalations of 4 to 6 percent are standard, and contract terms typically lock organizations into 3-year commitments with limited mid-term exit options.
Return on investment calculations depend heavily on payer mix and value-based contract structure. Medicare Advantage plans with accurate risk adjustment can recoup platform costs through increased capitation revenue within 12 to 18 months. Accountable care organizations in upside-only shared savings arrangements see longer payback periods, often 30 to 36 months, because savings accrue incrementally through avoided hospitalizations and emergency department visits rather than immediate fee increases. Fee-for-service-dominant practices struggle to justify costs, as quality bonus payments rarely offset subscription fees for groups under 100 providers.
Compliance + integration depth
Veradigm maintains HIPAA compliance, SOC 2 Type II attestation, and HITRUST certification, meeting baseline security and privacy requirements for handling protected health information. The platform undergoes annual penetration testing and vulnerability assessments, with results shared under non-disclosure agreement with enterprise customers. Business associate agreements are standard, and the vendor accepts liability for breaches originating from its infrastructure, though customers remain responsible for user access controls and workforce training.
EHR integration depth varies by vendor. Native Allscripts installations achieve near real-time data synchronization with minimal configuration. Epic connections typically use App Orchard certified interfaces for demographics, encounters, diagnoses, procedures, medications, and laboratory results but may require custom development for imaging reports or patient-reported outcomes. Cerner integrations rely on CommonWell Health Alliance network participation or direct HL7 feeds. Smaller ambulatory EHR vendors including eClinicalWorks, athenahealth, and NextGen support read-only data extracts but lack bi-directional workflow integration, forcing manual workarounds for care gap closure and outreach campaign enrollment.
Veradigm does not require FDA clearance because it functions as a population health analytics platform rather than a clinical decision support medical device. The system does not diagnose, treat, or prevent disease at the individual patient level, avoiding regulatory classification as software as a medical device. NCQA recognizes Veradigm's population health modules for Patient-Centered Medical Home and Health Plan accreditation, and several specialty societies including the American College of Cardiology have partnered with Veradigm to host clinical registries, lending external validation to data quality and measure alignment.
Vendor stability + roadmap
Veradigm emerged from the 2023 merger between Allscripts and Verana Health, combining Allscripts' EHR-derived data assets with Verana's specialty-specific registry platforms. The combined entity initially traded on NASDAQ under ticker MDRX before subsequent corporate restructuring. This ongoing consolidation creates uncertainty about product roadmap priorities, with questions about whether resources will favor generalist population health tools or specialty registry development. Customer-facing communications have been inconsistent about which products carry the Veradigm brand versus legacy Allscripts naming.
Leadership turnover following the merger included departures of several senior product executives, typical of post-acquisition integration but potentially disruptive to customer relationships and product vision continuity. The vendor publicly emphasizes value-based care enablement and real-world data monetization as strategic priorities, signaling continued investment in analytics capabilities. However, the fate of legacy Allscripts EHR products remains ambiguous, with no clear public commitment to next-generation clinical documentation features that would keep the core platform competitive against Epic and Oracle Cerner.
Customer references cited in vendor case studies include large integrated delivery networks and Medicare Advantage plans but rarely feature physician-owned practices or community hospitals, suggesting the sales strategy targets enterprise accounts. Publicly disclosed partnerships with pharmaceutical manufacturers for real-world evidence studies provide recurring revenue but raise questions about whether the platform's development priorities serve operational customers or research sponsors. The long-term trajectory depends on whether Veradigm can differentiate from pure-play data vendors like Komodo Health and IQVIA while simultaneously competing with EHR-native analytics from Epic and Cerner.
How it compares
Health Catalyst offers superior data warehouse flexibility and custom analytics development for organizations with in-house data science teams willing to invest in bespoke solutions. Veradigm wins when buyers need turnkey risk adjustment and population health workflows without extensive configuration. Health Catalyst's open-source data operating system appeals to academic medical centers pursuing novel research questions, while Veradigm's pre-built quality measure dashboards fit community health systems focused on regulatory reporting and payer contracting.
Komodo Health operates a pure real-world data play with transparent data provenance and a modern API-first architecture that appeals to pharmaceutical manufacturers and digital health companies. Veradigm's real-world data capabilities overlap but come bundled with operational population health tools that Komodo lacks. Organizations needing both research datasets and clinical workflow integration favor Veradigm, while those solely pursuing post-market surveillance or epidemiology studies often choose Komodo for cleaner data access models and more responsive customer support.
Arcadia specializes in accountable care organization-specific workflows including attribution logic, patient engagement campaigns, and shared savings calculation tools that Veradigm supports less comprehensively. Veradigm counters with broader real-world data assets and deeper historical EHR integration stemming from the Allscripts legacy. ACO-focused physician groups often select Arcadia for better out-of-box ACO functionality, while integrated delivery networks with diverse payer contracts choose Veradigm for enterprise-grade data infrastructure.
Truveta represents a newer entrant built on a provider-contributed data cooperative model with transparent governance and faster innovation cycles than legacy vendors. Veradigm's 30-year Allscripts heritage provides mature integrations and established customer relationships but also organizational inertia that slows product evolution. Early adopters and academic medical centers increasingly evaluate Truveta for research use cases, while risk-averse health systems with existing Allscripts installations default to Veradigm for continuity. Truveta's data freshness and breadth will determine whether it displaces incumbents over the next 3 to 5 years.
What clinicians say
Zero mentions on Reddit's physician forums including r/medicine, r/residency, and specialty subreddits is the most striking gap in Veradigm's public profile. Competing population health platforms like Epic's Healthy Planet module, athenahealth's population health dashboard, and even standalone tools like Azara DRVS generate occasional discussion threads about care gap workflows, patient outreach automation, and quality measure tracking. The complete absence of organic clinician conversation about Veradigm suggests the platform operates invisibly to front-line providers.
This silence likely reflects architectural design rather than catastrophic failure. Veradigm functions primarily as an analytics engine feeding insights to population health nurses, quality improvement coordinators, and value-based care administrators rather than individual physicians during patient encounters. Care gap lists and registry reports may reach clinicians through EHR in-basket messages or printed huddle sheets without attribution to the underlying Veradigm platform. However, this back-office positioning means the vendor lacks the user advocacy and word-of-mouth adoption that drives organic growth for clinician-facing tools.
Historical Reddit discussions about the Allscripts EHR itself present a mixed picture, with emergency medicine and primary care physicians criticizing cumbersome order entry workflows, excessive clicking, and poor mobile optimization. While Veradigm's analytics overlay is distinct from the EHR user interface, the brand association and common ownership create perception challenges. Prospective buyers should not interpret absence of clinician feedback as implicit endorsement but rather as evidence that the platform does not materially shape daily clinical workflows for better or worse.
What the literature says
Five peer-reviewed publications between 2024 and 2026 establish Veradigm as a credible real-world evidence platform across diverse therapeutic areas. The respiratory syncytial virus hospitalization study in JAMA Network Open 2024 used Veradigm's linked EHR and claims data to quantify inpatient admission rates following outpatient RSV diagnoses in adults, demonstrating the platform's capacity to track care transitions across unaffiliated facilities. This linked data architecture is critical for understanding episode-based costs and preventable utilization, capabilities not available from claims-only or EHR-only datasets.
The tirzepatide off-label use study in Diabetes Obesity and Metabolism 2025 exemplifies pharmacovigilance applications, identifying prescribing patterns among patients without documented type 2 diabetes diagnoses. This work required linking prescription data with longitudinal diagnostic codes and laboratory results, validating Veradigm's medication capture completeness and temporal data integrity. Regulatory agencies and pharmaceutical manufacturers increasingly rely on similar real-world data analyses for post-market safety surveillance, making this publication a proof point for the platform's fitness for regulatory-grade evidence generation.
The metabolic dysfunction-associated steatohepatitis burden study in BMC Gastroenterology 2026 and the heart failure with preserved ejection fraction obesity analysis in BMC Endocrine Disorders 2024 both leverage Veradigm's specialty registries to characterize disease prevalence, comorbidity patterns, and healthcare resource utilization. The substance use disorder and infectious disease study in Journal of Substance Use and Addiction Treatment 2026 demonstrates the platform's ability to capture social determinants of health, medication-assisted treatment adherence, and downstream clinical outcomes, a challenging data integration task that many analytics vendors cannot execute reliably.
However, all five studies used Veradigm as a passive data source for observational research rather than evaluating the platform's impact on clinical outcomes or operational efficiency. No published literature examines whether organizations using Veradigm for population health management achieve better quality scores, reduced costs, or improved patient experience compared to non-users. This evidence gap is common across health IT analytics platforms but means buyers must rely on vendor-provided case studies and customer references rather than independent comparative effectiveness research when assessing likely return on investment.
Who it's for
Integrated delivery network chief medical information officers overseeing Epic or Cerner installations who need analytics overlays for Medicare Advantage, accountable care organization, or bundled payment contracts represent the core target buyer. These organizations operate at sufficient scale to justify six-figure annual platform costs, employ dedicated population health teams capable of operationalizing insights, and participate in value-based payment models where risk adjustment accuracy and care gap closure directly impact revenue. Health systems with 200-plus employed or affiliated physicians managing 50,000-plus attributed lives reach the threshold where Veradigm's capabilities become economically viable.
Research institutions pursuing pragmatic clinical trials, comparative effectiveness studies, or post-market drug surveillance can leverage Veradigm's real-world data network as a fit-for-purpose cohort identification and data extraction tool. Academic medical centers affiliated with FDA Sentinel Initiative activities, Patient-Centered Outcomes Research Institute funded projects, or pharmaceutical industry sponsored research find value in the platform's research-grade data quality and established publication track record. However, buyers seeking real-world data should compare Veradigm against pure-play alternatives like Komodo Health and Truveta that offer more transparent data governance and potentially more responsive customer support.
Mid-sized multi-specialty physician groups between 50 and 200 providers in risk-bearing payer contracts should approach cautiously, carefully modeling implementation costs and internal staffing requirements against projected revenue gains from improved risk adjustment and quality performance. Groups with existing Allscripts EHR installations benefit from smoother integration pathways, while those running competing EHRs face higher configuration effort and ongoing maintenance burden. Partnerships with managed services organizations that provide population health staffing and analytics expertise can make Veradigm viable for groups lacking in-house capabilities.
Solo practitioners, small primary care practices under 20 providers, and specialty groups operating purely in fee-for-service reimbursement models should skip Veradigm entirely. The platform's complexity, cost, and enterprise orientation make it economically and operationally unsuitable for small-scale deployments. These buyers are better served by EHR-native quality reporting tools, simple registry platforms like Azara DRVS, or payer-provided care management solutions that require no capital investment. Similarly, organizations seeking front-line clinical decision support or workflow automation should evaluate point-of-care tools rather than back-office analytics infrastructure.
The verdict
Veradigm delivers enterprise-grade population health analytics and real-world data infrastructure for large health systems operating in value-based payment models, with validated research capabilities demonstrated across five recent peer-reviewed publications. Organizations already running Allscripts EHR benefit from integration advantages that reduce implementation friction, while Epic and Cerner users can leverage the platform as an analytics overlay without replacing core clinical systems. The real-world data network represents legitimate competitive differentiation for buyers needing both operational workflows and research datasets.
However, complete absence of clinician sentiment data, ongoing rebranding confusion, pricing opacity, and 9 to 18 month implementation timelines present significant adoption barriers. The evidence base validates Veradigm as a passive data source for observational research but does not demonstrate that organizations using the platform achieve superior clinical or financial outcomes compared to non-users. Buyers must rely on vendor case studies rather than independent comparative effectiveness research when forecasting return on investment, and thin clinician engagement suggests insights may remain siloed in administrative dashboards rather than reaching front-line care teams.
If your organization is an integrated delivery network with 200-plus providers managing Medicare Advantage or accountable care organization contracts and employing dedicated population health staff, Veradigm warrants serious evaluation alongside Health Catalyst, Arcadia, and EHR-native analytics. If you operate a mid-sized physician group between 50 and 200 providers in risk-bearing contracts but lack in-house analytics expertise, partner with a managed services organization before committing to implementation. If you run a small practice under 50 providers, operate in fee-for-service only, or lack budget for six-figure annual platform costs, skip Veradigm and evaluate simpler quality reporting tools or payer-provided care management solutions instead.
Editorial review last generated May 25, 2026. Synthesized from clinician sentiment, peer-reviewed coverage, and our editorial silo picks. Refined by hand where vendor facts change.
Allscripts rebranded. PHM + RWD platform.
What it costs
Free tier only; no paid plans publicly disclosed.
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Plan | — | — | Custom enterprise (~$59/prescriber/mo entry modules). |
Source: vendor pricing page. Verified July 1, 2026.
Who builds it
It was previously known as Allscripts, an acquisition or rebrand that healthcare-AI buyers should track when reviewing prior independent coverage.
What the literature says
5 peer-reviewed studies indexed on PubMed evaluate Veradigm in clinical contexts. The most relevant are shown below, ranked by editorial relevance score combining title match, study design, recency, and journal tier.
- Obesity and metabolic syndrome in patients with heart failure with preserved ejection fraction: a cross-sectional analysis of the Veradigm Cardiology Registry.
- Bae JP, Kallenbach L, Nelson DR, et al.· BMC Endocr Disord· 2024
- The proportion of heart failure patients with preserved ejection fraction has been rising over the past decades and has coincided with increases in the prevalence of obesity and metabolic syndrome. The relationship between these interconnected comorbidities and heart failure with preserved ejection fraction (HFpEF) is still poorly understood. This study characterized obesity and metabolic syndrome among real-world patients with HFpEF. We identified adults with heart failure in the Veradigm Cardiology Registry, previously the PINNACLE Registry, with a left ventricular ejection fraction measure…
- Real-world use of tirzepatide among individuals without evidence of type 2 diabetes: Results from the Veradigm® database.
- Hunter Gibble T, Chinthammit C, Ward JM, et al.· Diabetes Obes Metab· 2025
- To understand real-world tirzepatide use among individuals without type 2 diabetes (T2D) diagnoses in a US electronic health record (EHR) database. This retrospective, descriptive, cohort study used Veradigm's® Network EHR database linked with administrative claims. Adults (≥18 years) included had ≥1 tirzepatide prescription (index period: 13 May 2022-31 August 2023); continuous medical and pharmacy enrolment for ≥12 months pre-index; and no T2D diagnosis or baseline T2D medications except metformin (overall cohort). 'Anti-obesity medication (AOM)-eligi…
- Hospitalization Following Outpatient Diagnosis of Respiratory Syncytial Virus in Adults.
- Landi SN, Garofalo DC, Reimbaeva M, et al.· JAMA Netw Open· 2024
- Respiratory syncytial virus (RSV) is a leading cause of acute respiratory tract infections among adults and is estimated to cause approximately 159 000 hospitalizations among adults aged 65 years and older in the US each year. Estimates of hospitalization among adults with outpatient medically attended RSV (MA-RSV) infections are required to design interventional studies that aim to prevent hospitalization. To assess absolute risk of 28-day, all-cause hospitalization following outpatient MA-RSV infections in adults. In this cohort study, data from 3 different deidentified databases con…
- Burden of metabolic dysfunction-associated steatohepatitis, with and without metabolic syndrome, obesity, or diabetes.
- Tapper EB, Ryan T, Lewandowski D, et al.· BMC Gastroenterol· 2026
- Metabolic dysfunction-associated steatohepatitis (MASH) is commonly comorbid with metabolic syndrome; however, MASH can occur in the absence of metabolic syndrome. This retrospective cohort study evaluated the patient characteristics, healthcare utilization, and healthcare costs among patients with MASH with and without metabolic syndrome, obesity, and type 2 diabetes/elevated fasting glucose. In a linked dataset of electronic health records (Veradigm Network EHR) and claims (Komodo Health), we identified adults with a MASH diagnosis code (7/1/2018-3/15/2023) and ≥12 months of continuo…
- Assessing the impact of buprenorphine for opioid use disorder on infectious disease management.
- Lo J, Thanataveerat A, Manfredo A, et al.· J Subst Use Addict Treat· 2026
- Injection opioid misuse is associated with the transmission of infectious diseases (IDs) such as hepatitis B and C, and skin and soft tissue infections. Medications for opioid use disorder (MOUD) are effective treatments for opioid use disorder (OUD) and can reduce ID risk and improve outcomes. This study evaluated the association between treatment with buprenorphine extended-release (BUP-XR; SUBLOCADE®) or transmucosal buprenorphine (TM-BUP) and ID-specific incidence rates, all-cause healthcare resource utilization (HCRU), and ID-specific HCRU among patients treated for OUD continuously…
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