Kardia 12L vs Epic Sepsis Model
The Epic Sepsis Model is delivered within Epic licensing, and its price is not stated. Hospitals running Epic get a score that recalculates every 15 minutes for adult inpatients and ED patients, with alert thresholds each hospital sets. Independent results differ by version. At Michigan Medicine, 38,455 hospitalizations gave version 1 an AUROC of 0.63, and it missed 67% of sepsis cases. A 2026 prospective study of version 2 across four US systems found an AUROC of 0.82 to 0.92 with a positive predictive value of 0.13 to 0.26, so most alerts do not mark sepsis. openFDA lists no clearance for the Sepsis Model, while Epic's separate Deterioration Index Version 2 holds one (K260008).
Kardia 12L is a portable 12-lead ECG listed at $2,295, and the page does not say whether that recurs. It includes KardiaPro access and a 3-year warranty, and a cardiology clinic is the natural buyer. A hospital that runs Epic and a clinic that wants ECG tracings are separate purchasers.
Decision support · Reviewed November 2, 2026
Kardia 12L
by AliveCor
Portable 12-lead ECG device with FDA-cleared AI interpretation, sold to clinicians with KardiaPro patient management access.
Epic Sepsis Model
by Epic Systems
Sepsis risk score calculated every 15 minutes inside the Epic EHR, with alert thresholds set by each hospital.
When to pick each one
Kardia 12L
- $2,295 listed, KardiaPro and 3-year warranty included
- 12-lead ECG with FDA-cleared AI, per the vendor
Epic Sepsis Model
- Sepsis score inside the Epic chart
- Hospital sets its own alert threshold
- Independent multicentre validation of version 2
Score
Each row shows points earned of points available under the published rubric.
Kardia 12L
38of 100
Epic Sepsis Model
41of 100
| Dimension | Kardia 12L | Epic Sepsis Model | Difference |
|---|---|---|---|
| FDA clearance | 12 / 12 | 0 / 12 | +12 |
| HIPAA / SOC2 / BAA | 10 / 10 | 0 / 10 | +10 |
| EHR integrations (count) | 0 / 5.6 | 0 / 5.6 | 0 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 0 / 4.8 | 0 / 4.8 | 0 |
| Bidirectional write-back | 0 / 1.2 | 0 / 1.2 | 0 |
| Peer-reviewed papers | 0 / 21 | 21 / 21 | -21 |
| RCT / meta-analysis / systematic review | 0 / 9 | 9 / 9 | -9 |
| Funding & adoption signal | 8.4 / 12 | 3 / 12 | +5.4 |
| Pricing transparency | 1.3 / 2.5 | 1.3 / 2.5 | 0 |
| Years in market | 0 / 6 | 0 / 6 | 0 |
Scroll horizontally to see every column.
Pricing
Kardia 12L
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Kardia 12L | n/a | n/a | Includes the device, KardiaStation app, KardiaPro access and a 3-year warranty, with a 90-day return policy. Two-week trial for eligible U.S. HCPs by form. The page does not state whether the price is one-time or recurring. |
Epic Sepsis Model
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. Delivered within Epic licensing. |
Evidence
Kardia 12L
FDA decisions
K252589 (opens in new tab)510(k)2026-01-09
Corvair Monza
K231010 (opens in new tab)510(k)2024-06-07
Corvair
K232035 (opens in new tab)510(k)2024-06-07
Impala
K220350 (opens in new tab)510(k)2022-05-25
KardiaMobile 6L
K212662 (opens in new tab)510(k)2022-04-26
AliveCor QT Service
Show 14 more
K211668 (opens in new tab)510(k)2021-11-30
KardiaMobile Card
K210753 (opens in new tab)510(k)2021-06-30
KardiaMobile 6L
K201985 (opens in new tab)510(k)2020-11-12
KardiaAI
K191406 (opens in new tab)510(k)2020-01-24
KardiaMobile, KardiaStation
K183319 (opens in new tab)510(k)2019-05-10
Triangle System
K181823 (opens in new tab)510(k)2019-04-12
KardiaAI
K182396 (opens in new tab)510(k)2019-04-12
KardiaMobile, KardiaStation
K171816 (opens in new tab)510(k)2017-11-16
Kardia Band System
K142743 (opens in new tab)510(k)2015-01-27
AliveCor Heart Monitor
K142672 (opens in new tab)510(k)2014-12-03
AliveCor Heart Monitor
K140933 (opens in new tab)510(k)2014-08-15
AliveCor Heart Monitor
K130921 (opens in new tab)510(k)2014-02-06
AliveCor Heart Monitor
K130409 (opens in new tab)510(k)2013-09-06
AliveCor Heart Monitor
K122356 (opens in new tab)510(k)2012-11-19
AliveCor Heart Monitor for iPhone
Epic Sepsis Model
FDA decisions
No FDA decision cited in our research as of November 2, 2026.
Peer-reviewed
5 PubMed records name Epic Sepsis Model.
- A Systematic Review and Meta-analysis of Externally Validated Epic Clinical Decision Support Tools. (opens in new tab)
- Evaluation of Sepsis Prediction Models before Onset of Treatment. (opens in new tab)
- Multicenter Prospective Validation of an Updated Proprietary Sepsis Prediction Model. (opens in new tab)
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | Kardia 12L | Epic Sepsis Model |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Not specified | Not specified |
| Founded | n/a | n/a |
| HQ | US | US |
Scroll horizontally to see both columns.
Common questions
Open the full decision support comparison
Differential diagnosis, treatment guidance, drug interactions, evidence-grounded Q&A. The CDS landscape ranges from the UpToDate gold standard to physician-only OpenEvidence. We compared what clinicians actually use.