Epic Sepsis Model vs Implicity

A 2023 Europace paper on an AI algorithm for insertable cardiac monitors, written by Implicity authors, covered 546 patients and 879 abnormal episodes and reported 76.0 percent specificity and 98.6 percent sensitivity against an adjudication committee. A second 2023 paper, on alert filtering, also has Implicity authors. The vendor adds that 75 percent of SignalHF alerts before a hospitalization came at least 14 days ahead, a figure from its own press release.

Hospital device clinics that follow patients with implanted devices remotely buy Implicity. It holds K210543 (2021), K230842 for SignalHF (October 2023) and K253463 for the ILR ECG Analyzer (July 2026). Its home page shows five device makers, names no EHR and gives no price.

Epic sites score admitted patients with the Epic Sepsis Model, a different purchase from a device clinic's remote follow-up. In 2021 its first version scored an AUROC of 0.63 at Michigan Medicine and missed two thirds of sepsis cases. The 2026 prospective study of version 2 across four US systems reported AUROC of 0.82 to 0.92 but PPV of 0.13 to 0.26 and a high alert burden.