Zio vs Octagos
Zio is a patch worn on the skin. A deep neural network analyzes the recording in the cloud, qualified cardiac technicians validate the preliminary findings, and a physician report follows. The publicly traded parent, iRhythm Holdings, bills payers through Medicare-enrolled IDTFs, and no public price is listed. OpenFDA lists 18 510(k) records, the latest being the ZEUS Platform, K252859, decided in May 2026. A cardiology practice ordering ambulatory ECG monitoring for suspected arrhythmias buys it.
Octagos, a Houston company founded by practicing electrophysiologist Shanti Bansal, MD, works on what implanted pacemakers and defibrillators transmit. Clinics following those devices are its customers, and a practice that also runs an ambulatory ECG program could buy both for separate workloads. Its pricing page names four tiers, Pro as software only, Premium adding clinical and patient engagement services, Flex for on-demand services and Custom. Billing options are per billable transmission, a fixed monthly fee or a custom plan. The vendor claims an average of 21 days to EHR go-live.
Decision support · Reviewed November 2, 2026
Zio
by iRhythm Technologies · founded 2006
Zio ECG patch service: a deep-learning algorithm flags arrhythmias, cardiac technicians validate them, and a physician report follows.

Octagos
by Octagos
Remote cardiac device monitoring where AI triages implantable device transmissions and US specialists review them, for cardiology clinics.
When to pick each one
Zio
- Wear-and-send patch with technician review
- 18 FDA 510(k) records on openFDA
- Billed through Medicare-enrolled IDTFs
Octagos
- Pro tier is software only
- Vendor says 21 days average to EHR go-live
- Usage-based, fixed monthly or custom billing
Score
Each row shows points earned of points available under the published rubric.
Zio
69of 100
Octagos
43of 100
| Dimension | Zio | Octagos | Difference |
|---|---|---|---|
| FDA clearance | 12 / 12 | 0 / 12 | +12 |
| HIPAA / SOC2 / BAA | 0 / 10 | 10 / 10 | -10 |
| EHR integrations (count) | 0 / 5.6 | 2.8 / 5.6 | -2.8 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 0 / 4.8 | 4.8 / 4.8 | -4.8 |
| Bidirectional write-back | 0 / 1.2 | 0 / 1.2 | 0 |
| Peer-reviewed papers | 21 / 21 | 14.7 / 21 | +6.3 |
| RCT / meta-analysis / systematic review | 9 / 9 | 0 / 9 | +9 |
| Funding & adoption signal | 8.4 / 12 | 3 / 12 | +5.4 |
| Pricing transparency | 1.3 / 2.5 | 1.3 / 2.5 | 0 |
| Years in market | 6 / 6 | 0 / 6 | +6 |
Scroll horizontally to see every column.
Pricing
Zio
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. |
Octagos
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. |
Evidence
Zio
FDA decisions
K252859 (opens in new tab)510(k)2026-05-29
ZEUS Platform (FG0501US, DQK)
K243650 (opens in new tab)510(k)2025-08-15
Zio monitor (DFG0001)
K240177 (opens in new tab)510(k)2024-10-30
Zio AT device (A100A1001, DSI)
K240029 (opens in new tab)510(k)2024-10-21
Zio AT device (A100A1001, QYX)
K222389 (opens in new tab)510(k)2023-02-15
ZEUS System
Show 13 more
K213409 (opens in new tab)510(k)2022-07-19
ZEUS System (Zio Watch)
K202359 (opens in new tab)510(k)2021-05-21
Zio Monitor
K202527 (opens in new tab)510(k)2021-05-21
ZEUS System
K190593 (opens in new tab)510(k)2019-08-23
Zio XT ECG Monitoring System, Zio AT
K181502 (opens in new tab)510(k)2018-08-29
Zio AT ECG Monitoring System, ZEUS System
K163512 (opens in new tab)510(k)2017-06-02
Zio AT ECG Monitoring System
K143513 (opens in new tab)510(k)2015-06-19
ZIO SR ECG Monitoring Service
K142681 (opens in new tab)510(k)2014-11-21
ZEUS System
K121319 (opens in new tab)510(k)2012-07-18
ZIO PATCH
K113862 (opens in new tab)510(k)2012-02-06
ZIO PATCH
K091075 (opens in new tab)510(k)2009-07-21
ZEUS (ZIO ECG UTILIZATION SERVICE) SYSTEM
K090363 (opens in new tab)510(k)2009-05-08
ZIO PATCH Z100
K081471 (opens in new tab)510(k)2008-06-24
ECARD AND CCARD
Peer-reviewed
5 PubMed records name Zio.
- Physical activity cut-points for older adults using the Zio XT onboard accelerometer. (opens in new tab)
- Validation of a Zio XT Patch Accelerometer for the Objective Assessment of Physical Activity in the Atherosclerosis Risk in Communities (ARIC) Study. (opens in new tab)
- Zio® XT Patches in Pediatrics During the COVID-19 Pandemic: Comparisons Between In-Person and Mail-Home Application. (opens in new tab)
Octagos
FDA decisions
No FDA decision cited in our research as of November 2, 2026.
Peer-reviewed
2 PubMed records name Octagos.
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | Zio | Octagos |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Not specified | Epic, Oracle Health, athenahealth, medent, NextGen |
| Founded | 2006 | n/a |
| HQ | US | US |
Scroll horizontally to see both columns.
Common questions
Open the full decision support comparison
Differential diagnosis, treatment guidance, drug interactions, evidence-grounded Q&A. The CDS landscape ranges from the UpToDate gold standard to physician-only OpenEvidence. We compared what clinicians actually use.
