Isabel Healthcare vs Triomics
Triomics serves trial coordinators at cancer centers. PRISM screens upcoming patients against every active trial overnight and returns a cited worklist, and the vendor says it is approved on the Epic App Marketplace and lists OncoEMR and iKnowMed beside Epic. MSK announced in November 2025 that it would deploy the platform and discloses financial interests in Triomics. The vendor puts matching accuracy near 95%, citing a 2024 npj Digital Medicine paper on PRISM.
Isabel serves an individual physician working up an unfamiliar presentation, and the two share no purchasing path. Standard is $149 per year, Premium $199 and residents pay $49, with a 30-day trial. The vendor says Cerner's App Gallery carries it and Epic clients get info-button access. In a 2025 comparison of 100 rare-disease patients, its top ten matched at least one case-conference diagnosis in 28%, and the authors say history filtering may limit standalone use.
Decision support · Reviewed November 2, 2026

Isabel Healthcare
by Isabel Healthcare · founded 1999
Differential-diagnosis generator with self-triage and educator products. The vendor says it is used in over 90 countries and 14 languages.

Triomics
by triomics inc.
Oncology AI agents that match patients to clinical trials, prepare visits and curate cancer registries from notes, reports and faxes.
When to pick each one
Isabel Healthcare
- Standard plan $149 per year, residents $49
- Vendor lists Cerner App Gallery and Epic info-button access
- 30-day free trial on the individual plans
Triomics
- Epic App Marketplace approval, per the vendor
- Overnight trial screening for cancer center coordinators
- OncoEMR and iKnowMed listed alongside Epic
Score
Each row shows points earned of points available under the published rubric.
Isabel Healthcare
35of 100
Triomics
12of 100
| Dimension | Isabel Healthcare | Triomics | Difference |
|---|---|---|---|
| FDA clearance | 0 / 12 | 0 / 12 | 0 |
| HIPAA / SOC2 / BAA | 0 / 10 | 0 / 10 | 0 |
| EHR integrations (count) | 0 / 5.6 | 2.8 / 5.6 | -2.8 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 0 / 4.8 | 3.4 / 4.8 | -3.4 |
| Bidirectional write-back | 0 / 1.2 | 0 / 1.2 | 0 |
| Peer-reviewed papers | 14.7 / 21 | 0 / 21 | +14.7 |
| RCT / meta-analysis / systematic review | 0 / 9 | 0 / 9 | 0 |
| Funding & adoption signal | 6 / 12 | 3 / 12 | +3 |
| Pricing transparency | 2.5 / 2.5 | 1.3 / 2.5 | +1.3 |
| Years in market | 6 / 6 | 0 / 6 | +6 |
Scroll horizontally to see every column.
Pricing
Isabel Healthcare
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Standard | n/a | $149 | EUR 139 incl. VAT. 30-day free trial. |
| Premium | n/a | $199 | EUR 179 incl. VAT. Adds an LLM layer (English only). |
| Student / resident | n/a | $49 | Not available to EU students. 50% discount for listed emerging economies. |
| Institutional | n/a | n/a | Demo request, no public price. The API has been available since 2010. |
Triomics
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. Demo request and synthetic-data sandbox offered. |
Evidence
Isabel Healthcare
FDA decisions
No FDA decision cited in our research as of October 20, 2026.
Peer-reviewed
2 PubMed records name Isabel Healthcare.
- Cracking the code: a head-to-head comparison of expert clinicians and artificial intelligence in diagnosing rare diseases. (opens in new tab)
- Is language an issue? Accuracy of the German computerized diagnostic decision support system ISABEL and cross-validation with the English counterpart. (opens in new tab)
Triomics
FDA decisions
No FDA decision cited in our research as of November 2, 2026.
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | Isabel Healthcare | Triomics |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Not specified | Epic, OncoEMR, iKnowMed, Cerner |
| Founded | 1999 | n/a |
| HQ | UK | US |
Scroll horizontally to see both columns.
Common questions
Open the full decision support comparison
Differential diagnosis, treatment guidance, drug interactions, evidence-grounded Q&A. The CDS landscape ranges from the UpToDate gold standard to physician-only OpenEvidence. We compared what clinicians actually use.
