Nanox.AI vs Optellum Virtual Nodule Clinic
A hospital with a low-dose CT lung screening program can spend on either. Nanox's HealthCCSng reads non-gated, non-contrast chest CT in adults 30 to 85 and returns an exact calcium score with a four-category result (K241440, decided August 19, 2024). A Nanox case study published by the vendor reports 31.0% moderate-to-severe calcification among Atlantic Health's lung screening patients.
Optellum's Virtual Nodule Clinic (K202300, decided March 5, 2021) tracks and characterizes incidentally detected pulmonary nodules, and its CNN risk score goes to pulmonologists and radiologists. Pulmonology-led nodule clinics are where it sits, and its reimbursement page lists CPT Category III codes 0721T and +0722T. Nanox's HealthCCSng, HealthOST and HealthFLD target calcium, bone and liver, so a nodule clinic has little to run on them. A screening program that wants coronary calcium from the same scans finds Optellum falling behind, since its clearance covers pulmonary nodules.
Radiology · Reviewed November 2, 2026

Nanox.AI
by Nano-X Imaging
CT AI for opportunistic screening: coronary calcium, vertebral fractures and liver fat on routine CT scans, for radiology departments.

Optellum Virtual Nodule Clinic
by Optellum · founded 2016
FDA-cleared AI that scores lung cancer risk for CT lung nodules and tracks them, for pulmonologists and radiology departments.
When to pick each one
Nanox.AI
- Exact calcium score from non-gated, non-contrast chest CT
- Adults 30 to 85, K241440
Optellum Virtual Nodule Clinic
- Characterizes incidentally detected nodules on lung CT
- CPT Category III codes 0721T and +0722T
- ISO 13485 and ISO/IEC 27001 listed
Score
Each row shows points earned of points available under the published rubric.
Nanox.AI
35of 100
Optellum Virtual Nodule Clinic
35of 100
| Dimension | Nanox.AI | Optellum Virtual Nodule Clinic | Difference |
|---|---|---|---|
| FDA clearance | 18 / 18 | 18 / 18 | 0 |
| HIPAA / SOC2 / BAA | 0 / 10 | 0 / 10 | 0 |
| EHR integrations (count) | 0 / 4.2 | 0 / 4.2 | 0 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 0 / 2.4 | 0 / 2.4 | 0 |
| Peer-reviewed papers | 0 / 18.2 | 0 / 18.2 | 0 |
| RCT / meta-analysis / systematic review | 0 / 7.8 | 0 / 7.8 | 0 |
| Funding & adoption signal | 8.4 / 12 | 3 / 12 | +5.4 |
| Pricing transparency | 2.5 / 5 | 2.5 / 5 | 0 |
| Years in market | 0 / 6 | 6 / 6 | -6 |
Scroll horizontally to see every column.
Pricing
Nanox.AI
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. |
Optellum Virtual Nodule Clinic
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. Reimbursement fact, not a price: CPT Category III codes 0721T and +0722T; Medicare hospital outpatient APC 1508 rate $650.50 for 2026 (national average, before deductibles). |
Evidence
Nanox.AI
FDA decisions
K241440 (opens in new tab)510(k)2024-08-19
HealthCCSng
K233080 (opens in new tab)510(k)2024-02-08
HealthFLD
K213944 (opens in new tab)510(k)2022-04-22
HealthOST
K211803 (opens in new tab)510(k)2021-12-15
HealthPPT
K210085 (opens in new tab)510(k)2021-09-15
HealthCCSng
Show 7 more
K202487 (opens in new tab)510(k)2020-12-04
HealthJOINT
K200905 (opens in new tab)510(k)2020-07-16
HealthMammo
K192901 (opens in new tab)510(k)2020-05-12
HealthVCF
K192320 (opens in new tab)510(k)2019-11-26
HealthCXR
K190424 (opens in new tab)510(k)2019-06-13
HealthICH
K190362 (opens in new tab)510(k)2019-05-06
HealthPNX
K172983 (opens in new tab)510(k)2018-06-13
HealthCCS
Optellum Virtual Nodule Clinic
FDA decisions
K202300 (opens in new tab)510(k)2021-03-05
Optellum Virtual Nodule Clinic, Optellum software, Optellum platform
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | Nanox.AI | Optellum Virtual Nodule Clinic |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Not specified | Not specified |
| Founded | n/a | 2016 |
| HQ | n/a | GB |
Scroll horizontally to see both columns.
Common questions
Open the full radiology comparison
Acute-care triage, mammography screening, CCTA plaque analysis, mobile MRI. 30+ FDA-cleared platforms across stroke, oncology, cardiac. Enterprise sales only — we compared what's deployed where.
