MedAI Verdict
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Nanox.AI vs Pearl

Nanox.AI reads CT scans a hospital already has. HealthCCSng measures coronary calcium on non-gated chest CT, HealthOST flags vertebral height loss and bone density, and HealthFLD measures liver density. Pearl reads dental radiographs and dental CBCT. A health system that wants unrecognized chronic disease flagged on routine CT is the Nanox.AI customer, and a dental practice is Pearl's, so each answers to a different budget holder.

On the Nanox side, the vendor says seven FDA clearances while openFDA lists twelve AI records under the Zebra, Nanoxai and Nano-X AI names, and the AI page presents three current solutions. A 2025 HealthOST validation reported 92.0% sensitivity at the 20% height-loss threshold, with the abstract's specificity figures beginning at 52.7%.

Pearl's FAQ names the systems it connects to, among them DEXIS, Carestream, Romexis, Open Dental and Eaglesoft. Second Opinion 3D, cleared in May 2025 as K243989, marks dentition, the maxillary sinus and the inferior alveolar canal on CBCT.

Radiology · Reviewed November 2, 2026

Nanox.AI logo

Nanox.AI

by Nano-X Imaging

CT AI for opportunistic screening: coronary calcium, vertebral fractures and liver fat on routine CT scans, for radiology departments.

Pearl logo

Pearl

by Pearl Inc. · founded 2019

FDA-cleared dental x-ray AI (Second Opinion) that marks caries, bone loss and restorations, for dentists and DSOs.

When to pick each one

Nanox.AI

  • Coronary calcium, vertebral fracture and liver fat on CT
  • Twelve openFDA AI records under Zebra and Nanox names
Read the full Nanox.AI review

Pearl

  • Names DEXIS, Carestream, Open Dental and Eaglesoft
  • Dental CBCT review, K243989 May 2025
Read the full Pearl review

Score

Each row shows points earned of points available under the published rubric.

Nanox.AI

35of 100

Competitive

Pearl

33of 100

Competitive
Score by dimension for Nanox.AI and Pearl
DimensionNanox.AIPearlDifference
FDA clearance18 / 1818 / 180
HIPAA / SOC2 / BAA0 / 100 / 100
EHR integrations (count)0 / 4.20 / 4.20
Top-3 EHR coverage (Epic / Oracle / Athena)0 / 2.40 / 2.40
Peer-reviewed papers0 / 18.20 / 18.20
RCT / meta-analysis / systematic review0 / 7.80 / 7.80
Funding & adoption signal8.4 / 123 / 12+5.4
Pricing transparency2.5 / 52.5 / 50
Years in market0 / 64.2 / 6-4.2

Scroll horizontally to see every column.

How scores are computed

Pricing

Nanox.AI

TierMonthlyAnnualNotes
Enterprisen/an/aNo public price.

Pearl

TierMonthlyAnnualNotes
Enterprisen/an/aNo public price.

Evidence

Nanox.AI

FDA decisions

Show 7 more

Pearl

FDA decisions

Show 3 more

Compliance and integrations

Documented from each vendor’s own pages.

SpecNanox.AIPearl
Free tierNo / unverifiedNo / unverified
HIPAANo / unverifiedNo / unverified
SOC 2 Type IINo / unverifiedNo / unverified
EHR integrationsNot specifiedNot specified
Foundedn/a2019
HQn/aUS

Scroll horizontally to see both columns.

Common questions

Open the full radiology comparison

Acute-care triage, mammography screening, CCTA plaque analysis, mobile MRI. 30+ FDA-cleared platforms across stroke, oncology, cardiac. Enterprise sales only — we compared what's deployed where.