- No public price. Appliance tiers CIS-1, CIS-2 and CIS-3 are listed without prices. Demo via Calendly
- Not disclosed
- Not disclosed
- —
- 2023
- US


ThetaRho RISA
by ThetaRho · founded 2023 · US
Clinical research assistant that summarizes patient charts and answers clinician queries, sold on an on-premises appliance.
On this page
Not rated: too little independent evidence yet.
- Regulatory & Compliance0/13
No public HIPAA/SOC2/BAA attestation
- Clinical Integration0/38.2
No EHR integrations listed
- Evidence Strength0/10
No peer-reviewed coverage
- Vendor & Market6/18
Seed-stage or unfunded
- Sentiment & Transparency2.5/5
Pricing on request, no public amounts
▸ Show all 11 dimensions▾ Hide dimension detail
- HIPAA / SOC2 / BAA0/13
No public HIPAA/SOC2/BAA attestation
- EHR integrations (count)0/21
No EHR integrations listed
- Top-3 EHR coverage (Epic / Oracle / Athena)0/12
None of the top-3 EHRs covered
- Bidirectional write-back0/5
No bidirectional write-back documented
- Peer-reviewed papers0/7
No peer-reviewed coverage
- RCT / meta-analysis / systematic review0/3
No RCT, meta-analysis, or systematic review
- Funding & adoption signal3/12
Seed-stage or unfunded
- Years in market3/6
Founded 2023 (3 years)
- Pricing transparency3/5
Pricing on request, no public amounts
Clinical research assistant that summarizes patient charts and answers clinician queries, sold on an on-premises appliance.
No public price. Appliance tiers CIS-1, CIS-2 and CIS-3 are listed without prices. Demo via Calendly.
Evidence record
- Score computed November 2, 2026, method 1.2.0
- Review written November 2, 2026
MedAI Verdict, ThetaRho RISA record, https://medaiverdict.com/tools/thetarho, version November 2, 2026
Bottom line
ThetaRho's RISA (Clinical Research Assistant) answers clinician questions over a patient's chart, summarizes it and drafts documents for physician approval. The vendor homepage now sells RISA bundled on every unit of its Clinical Intelligence System (CIS), an on-premises appliance that runs AI models inside the customer's network. The appliance starts at a tier for one to three providers and runs up to a health system or research network. Research teams and health-system IT groups are the audience the homepage frames. The price is not published.
What does RISA do, according to its page?
The RISA page describes four functions. Retrieve answers questions from vitals, labs, medications, notes, imaging and documents drawn from the EHR, CommonWell, TEFCA and health information exchanges, reading PDFs, CCDAs and scans. Investigate searches literature, guidelines and drug databases with citations. Synthesize produces pre-visit and since-last-visit summaries, timelines and care gaps. Act drafts notes, referral summaries, prior-authorization justifications and billing recommendations, with physician approval required.
The page says every claim is marked grounded (traced to the chart) or ungrounded (needs validation), and lists editions for cardiology, oncology, primary care, gynecology, pulmonology and gastroenterology.
What is the CIS appliance?
The homepage says CIS "runs local AI models and apps on one appliance inside your network". CIS-1 is for one to three providers, CIS-2 for a department and CIS-3 for a health system or research network. The vendor says PHI never leaves the network and air-gapped operation is possible, and that AI runs on the appliance's GPUs with fixed costs and no per-token billing. A demo is booked through Calendly.
Which EHRs, and what security status?
The vendor names no EHR on its homepage, About page or RISA page, only CommonWell, TEFCA and connected exchanges, and it does not name FHIR. CB Insights calls the product FHIR-native. HIPAA and SOC 2 status is unconfirmed. Neither FDA nor CE status is stated.
Who is ThetaRho?
Search profiles from CB Insights and Nasdaq Private Market place ThetaRho.ai in San Jose, California, founded in 2023, with Kannan Govindarajan as CEO and founder and Ramani Narayan on the board. PitchBook lists a $750K early-stage deal and ten employees. A CB Insights item mentions an athenahealth Marketplace partnership that the vendor's site does not confirm. The homepage carries three unnamed physician testimonials.
The verdict
Whether RISA is still sold on its own, or only inside a CIS appliance, is not stated on the homepage. The buyer the pages describe is a team that wants chart questions answered by models running on its own network.
Editorial review last generated November 2, 2026. Synthesized from clinician sentiment, peer-reviewed coverage, and our editorial silo picks. Refined by hand where vendor facts change.
What it costs
All tiers are custom-quoted. The vendor does not publish per-provider list pricing.
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | Not stated | Not stated | No public price. Appliance tiers CIS-1, CIS-2 and CIS-3 are listed without prices. Demo via Calendly |
Source: vendor pricing page. Last checked November 2, 2026.
Who builds it
ThetaRho RISA (ThetaRho) was founded in 2023 in US, putting it 3 years into market.

