eCART vs OpenEvidence
OpenEvidence costs a physician nothing. Access is free to NPI-verified clinicians and funded by advertising, which secondary sources say is mostly pharmaceutical. Its security page states HIPAA compliance, a standard BAA and SOC 2 Type II. Reddit users in September 2025 reported journal bias and a chest x-ray and pulmonary embolism error, and a medRxiv pilot that is not peer reviewed reported accuracy of 31% on a quick search and 39.5% in Deep Consult on subspecialty scenarios. A family physician reaches for it between patients. AgileMD's eCART answers a different need, ward deterioration alerts for a hospital response team, and at Yale the vendor reports a 13% relative mortality reduction since go-live, while a third-party blog argues the response team matters as much as the score.
Decision support · Reviewed November 2, 2026
eCART
by AgileMD
Early warning software that scores hospitalized ward patients for risk of deterioration from EHR data, for use by trained clinicians.
OpenEvidence
by OpenEvidence · founded 2022
Free physician-only literature-grounded Q&A, 1M consults/day.
When to pick each one
eCART
- Deterioration alerts cleared in June 2024
- Vendor-reported 13% mortality reduction at Yale
OpenEvidence
- Free for NPI-verified physicians, ad-funded
- SOC 2 Type II and a standard BAA stated
- Cited answers with NEJM and JAMA content
Score
Each row shows points earned of points available under the published rubric.
eCART
56of 100
OpenEvidence
52of 100
| Dimension | eCART | OpenEvidence | Difference |
|---|---|---|---|
| FDA clearance | 12 / 12 | 0 / 12 | +12 |
| HIPAA / SOC2 / BAA | 10 / 10 | 0 / 10 | +10 |
| EHR integrations (count) | 0 / 5.6 | 0 / 5.6 | 0 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 0 / 4.8 | 0 / 4.8 | 0 |
| Bidirectional write-back | 0 / 1.2 | 0 / 1.2 | 0 |
| Peer-reviewed papers | 21 / 21 | 21 / 21 | 0 |
| RCT / meta-analysis / systematic review | 0 / 9 | 4.5 / 9 | -4.5 |
| Funding & adoption signal | 3 / 12 | 12 / 12 | -9 |
| Pricing transparency | 1.3 / 2.5 | 2.5 / 2.5 | -1.2 |
| Years in market | 0 / 6 | 4.2 / 6 | -4.2 |
Scroll horizontally to see every column.
Pricing
eCART
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. There is no pricing page; the site offers a demo request only. |
OpenEvidence
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Plan | n/a | n/a | Free for NPI-verified physicians (ad-funded). |
Evidence
eCART
FDA decisions
K233253 (opens in new tab)510(k)2024-06-21
eCARTv5 Clinical Deterioration Suite (eCART)
Peer-reviewed
5 PubMed records name eCART.
- Early Warning Scores With and Without Artificial Intelligence. (opens in new tab)
- Multicenter Development and Prospective Validation of eCARTv5: A Gradient Boosted Machine Learning Early Warning Score. (opens in new tab)
- DETERIO-LLM: enhancing traditional deterioration risk scores with clinical context and advanced reasoning. (opens in new tab)
OpenEvidence
FDA decisions
No FDA decision cited in our research as of October 20, 2026.
Peer-reviewed
5 PubMed records name OpenEvidence.
- Performance of Large Language Models on Diagnostic Radiology Board-Style Questions: A Comparative Evaluation of GPT-4o, Perplexity AI, and OpenEvidence. (opens in new tab)
- OpenEvidence. (opens in new tab)
- Concordance of ChatGPT, Gemini, Claude, and OpenEvidence with the 2024 AAOS guidelines on acute isolated meniscal pathology. (opens in new tab)
Community
20 posts sourced: 3 positive, 14 neutral, 3 negative.
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | eCART | OpenEvidence |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Not specified | Not specified |
| Founded | n/a | 2022 |
| HQ | US | US |
Scroll horizontally to see both columns.
Common questions
Open the full decision support comparison
Differential diagnosis, treatment guidance, drug interactions, evidence-grounded Q&A. The CDS landscape ranges from the UpToDate gold standard to physician-only OpenEvidence. We compared what clinicians actually use.