MedAI Verdict
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Avo vs SimpleSense

Nanowear's 303-subject prospective multicentre study of its cuffless blood pressure monitor (J Cardiovasc Transl Res 2025) came from vendor-affiliated authors, ran four weeks and was internal validation only, and the authors call for external validation. A 2022 Sci Rep paper on its multiparametric cloth-based SimpleSense estimating blood pressure carries the same Nanowear affiliation. The garment and its cloud analytics hold four FDA 510(k) clearances, the newest SimpleSense-BP in December 2023. The company is in Brooklyn and was founded in 2014, and listed funding is $1.52M over two rounds per Tracxn. A heart failure clinic or cardiology practice is the buyer, with no public price.

A medical director rolling out documentation and decision support looks to Avo, whose homepage figures are vendor claims with no study link: a 35% cut in note time per patient and $11.6M in annual savings at an ambulatory organization. One is remote cardiometabolic monitoring bought by a clinic, the other chart tooling bought by a health system.

Decision support · Reviewed November 2, 2026

Avo logo

Avo

by AvoMD

Guideline-based clinical decision support and EHR chart assistants for health systems, with ambient documentation.

SimpleSense logo

SimpleSense

by Nanowear · founded 2014

Cloth wearable with 510(k) cleared AI cloud analytics for remote cardiac monitoring and cuffless blood pressure.

When to pick each one

Avo

  • Vendor-claimed 35% less note time per patient
  • Documentation and decision support in one platform
Read the full Avo review

SimpleSense

  • Four FDA 510(k) clearances, cuffless blood pressure
  • Home heart failure monitoring with a cloth garment
  • 303-subject study, internal validation only
Read the full SimpleSense review

Score

Each row shows points earned of points available under the published rubric.

Avo

18of 100

Tracked

SimpleSense

49of 100

Solid choice
Score by dimension for Avo and SimpleSense
DimensionAvoSimpleSenseDifference
FDA clearance0 / 1212 / 12-12
HIPAA / SOC2 / BAA6 / 100 / 10+6
EHR integrations (count)1.7 / 5.60 / 5.6+1.7
Top-3 EHR coverage (Epic / Oracle / Athena)3.4 / 4.80 / 4.8+3.4
Bidirectional write-back0 / 1.20 / 1.20
Peer-reviewed papers0 / 2114.7 / 21-14.7
RCT / meta-analysis / systematic review0 / 94.5 / 9-4.5
Funding & adoption signal3 / 123 / 120
Pricing transparency1.3 / 2.51.3 / 2.50
Years in market0 / 66 / 6-6

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How scores are computed

Pricing

Avo

TierMonthlyAnnualNotes
Enterprisen/an/aNo public price. The pricing page returns 404; the site offers a demo booking only.

SimpleSense

TierMonthlyAnnualNotes
Enterprisen/an/aNo public price.

Compliance and integrations

Documented from each vendor’s own pages.

SpecAvoSimpleSense
Free tierNo / unverifiedNo / unverified
HIPAANo / unverifiedNo / unverified
SOC 2 Type IIYesNo / unverified
EHR integrationsEpic, athenahealth, MEDITECHNot specified
Foundedn/a2014
HQUSUS

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Common questions

Open the full decision support comparison

Differential diagnosis, treatment guidance, drug interactions, evidence-grounded Q&A. The CDS landscape ranges from the UpToDate gold standard to physician-only OpenEvidence. We compared what clinicians actually use.