Eko Health vs Epic Sepsis Model
Eko sells the CORE 300 digital stethoscope as a $199 one-time purchase, marked down from a $249 list price with no sale end date shown. Eko's AI needs the Eko+ membership at $119.99 per year, with a 14-day free trial. AFib detection requires the CORE 500, and the low ejection fraction tool runs on an ECG-capable stethoscope. Health systems reach SENSORA and Eko Telehealth through Contact Sales. Eko holds ten 510(k) records on openFDA.
The Epic Sepsis Model is a risk score delivered within Epic licensing, recalculated every 15 minutes, with alert thresholds the hospital sets. A clinician who auscultates buys from Eko, and an Epic customer's sepsis program uses the model, so a health system could own both without trading one for the other. An independent ED validation in the American Journal of Emergency Medicine (2025) of 35,076 encounters found AUROC of 0.77 for version 1 and 0.90 for version 2.
Decision support · Reviewed November 2, 2026

Eko Health
by Eko Health
Digital stethoscopes and an AI membership that detect heart murmurs, AFib and low ejection fraction for clinicians.

Epic Sepsis Model
by Epic Systems
Sepsis risk score calculated every 15 minutes inside the Epic EHR, with alert thresholds set by each hospital.
When to pick each one
Eko Health
- CORE 300 stethoscope at $199 one-time, list $249
- Eko+ AI membership at $119.99 per year
- Ten 510(k) records on openFDA
Epic Sepsis Model
- Score recalculated every 15 minutes inside Epic
- Version 2 AUROC 0.90 in an ED validation
- Delivered within Epic licensing
Score
Each row shows points earned of points available under the published rubric.
Eko Health
48of 100
Epic Sepsis Model
41of 100
| Dimension | Eko Health | Epic Sepsis Model | Difference |
|---|---|---|---|
| FDA clearance | 12 / 12 | 0 / 12 | +12 |
| HIPAA / SOC2 / BAA | 10 / 10 | 0 / 10 | +10 |
| EHR integrations (count) | 0 / 5.6 | 0 / 5.6 | 0 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 0 / 4.8 | 0 / 4.8 | 0 |
| Bidirectional write-back | 0 / 1.2 | 0 / 1.2 | 0 |
| Peer-reviewed papers | 8.4 / 21 | 21 / 21 | -12.6 |
| RCT / meta-analysis / systematic review | 0 / 9 | 9 / 9 | -9 |
| Funding & adoption signal | 8.4 / 12 | 3 / 12 | +5.4 |
| Pricing transparency | 1.3 / 2.5 | 1.3 / 2.5 | 0 |
| Years in market | 0 / 6 | 0 / 6 | 0 |
Scroll horizontally to see every column.
Pricing
Eko Health
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| CORE 300 digital stethoscope | n/a | n/a | Sale price, list price $249 struck through on the product page. Sale end date not shown. |
| Eko+ | n/a | n/a | Required for Eko AI. Renews automatically for the year. 14-day free trial, downgrade to Free before day 14. |
| Enterprise (SENSORA, Eko Telehealth) | n/a | n/a | No public price. Contact sales. |
Epic Sepsis Model
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. Delivered within Epic licensing. |
Evidence
Eko Health
FDA decisions
K261694 (opens in new tab)510(k)2026-07-23
CORE 300 Digital Stethoscope
K251494 (opens in new tab)510(k)2025-08-12
Eko Foundation Analysis Software with Transformers (EFAST)
K233409 (opens in new tab)510(k)2024-03-28
Eko Low Ejection Fraction Tool (ELEFT)
K233609 (opens in new tab)510(k)2024-03-28
CORE 500 Digital Stethoscope
K230111 (opens in new tab)510(k)2023-05-26
CORE 500 Digital Stethoscope
Show 5 more
K213794 (opens in new tab)510(k)2022-06-29
Eko Murmur Analysis Software (EMAS)
K200776 (opens in new tab)510(k)2020-04-06
Eko CORE
K192004 (opens in new tab)510(k)2020-01-15
Eko Analysis Software
K170874 (opens in new tab)510(k)2017-05-19
Eko Model E5 System (EME5), Eko DUO
K151319 (opens in new tab)510(k)2015-08-28
Eko Electronic Stethoscope System
Peer-reviewed
1 PubMed record names Eko Health.
Epic Sepsis Model
FDA decisions
No FDA decision cited in our research as of November 2, 2026.
Peer-reviewed
5 PubMed records name Epic Sepsis Model.
- A Systematic Review and Meta-analysis of Externally Validated Epic Clinical Decision Support Tools. (opens in new tab)
- Evaluation of Sepsis Prediction Models before Onset of Treatment. (opens in new tab)
- Multicenter Prospective Validation of an Updated Proprietary Sepsis Prediction Model. (opens in new tab)
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | Eko Health | Epic Sepsis Model |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Not specified | Not specified |
| Founded | n/a | n/a |
| HQ | US | US |
Scroll horizontally to see both columns.
Common questions
Open the full decision support comparison
Differential diagnosis, treatment guidance, drug interactions, evidence-grounded Q&A. The CDS landscape ranges from the UpToDate gold standard to physician-only OpenEvidence. We compared what clinicians actually use.
