Etiometry Platform vs Isabel Healthcare
Isabel Healthcare sells yearly subscriptions to individual clinicians and residents at public prices. DDx Companion Standard is $149 per year, Premium $199 per year, and the student or resident plan $49 per year, with a 30-day trial of the Companion. Institutions ask for a demo and connect through an API. The vendor says Isabel DDx is in the Cerner App Gallery, that Epic clients get info-button access, and that the correct disease lands in its top ten 96% of the time.
A 2025 Orphanet Journal of Rare Diseases study set it against an interdisciplinary case conference on 100 patients. A summary of the paper reports a top-ten match to at least one conference diagnosis in 28%, and the authors suggest history filtering limited it. An openFDA 510(k) search for "isabel" as applicant or device name returned no record.
The vendor describes Etiometry as a clinical intelligence platform for critical care clinicians, and an individual clinician on a $149 plan is not shopping for an ICU platform. Studies of the platform include a 2025 Critical Care Medicine paper on vasoactive infusion duration after pediatric cardiac surgery and a 2024 JTCVS Open validation of an oxygen-delivery index.
Decision support · Reviewed November 2, 2026

Etiometry Platform
by Etiometry · founded 2010
ICU data platform that aggregates monitor and EHR data and runs four FDA-cleared physiologic risk indices.

Isabel Healthcare
by Isabel Healthcare · founded 1999
Differential-diagnosis generator with self-triage and educator products. The vendor says it is used in over 90 countries and 14 languages.
When to pick each one
Etiometry Platform
- Critical care clinicians are the stated audience
- Indications span children to age 12 and adults
- Studies of the platform in Critical Care Medicine
Isabel Healthcare
- $149 or $199 per year, $49 for residents
- 30-day free trial
- Vendor says Cerner App Gallery and Epic info-button access
Score
Each row shows points earned of points available under the published rubric.
Etiometry Platform
38of 100
Isabel Healthcare
35of 100
| Dimension | Etiometry Platform | Isabel Healthcare | Difference |
|---|---|---|---|
| FDA clearance | 12 / 12 | 0 / 12 | +12 |
| HIPAA / SOC2 / BAA | 10 / 10 | 0 / 10 | +10 |
| EHR integrations (count) | 0 / 5.6 | 0 / 5.6 | 0 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 0 / 4.8 | 0 / 4.8 | 0 |
| Bidirectional write-back | 0 / 1.2 | 0 / 1.2 | 0 |
| Peer-reviewed papers | 0 / 21 | 14.7 / 21 | -14.7 |
| RCT / meta-analysis / systematic review | 0 / 9 | 0 / 9 | 0 |
| Funding & adoption signal | 3 / 12 | 6 / 12 | -3 |
| Pricing transparency | 1.3 / 2.5 | 2.5 / 2.5 | -1.2 |
| Years in market | 6 / 6 | 6 / 6 | 0 |
Scroll horizontally to see every column.
Pricing
Etiometry Platform
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. Demo request only. |
Isabel Healthcare
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Standard | n/a | $149 | EUR 139 incl. VAT. 30-day free trial. |
| Premium | n/a | $199 | EUR 179 incl. VAT. Adds an LLM layer (English only). |
| Student / resident | n/a | $49 | Not available to EU students. 50% discount for listed emerging economies. |
| Institutional | n/a | n/a | Demo request, no public price. The API has been available since 2010. |
Evidence
Etiometry Platform
FDA decisions
K254066 (opens in new tab)510(k)2026-04-03
Etiometry Platform
K241479 (opens in new tab)510(k)2025-02-12
Etiometry Platform (DAV 5.4 RAE 9.2)
K223578 (opens in new tab)510(k)2023-07-07
T3 Platform software
K213423 (opens in new tab)510(k)2023-01-06
T3 Platform software
K213230 (opens in new tab)510(k)2022-06-22
T3 Platform Software
Show 6 more
K202306 (opens in new tab)510(k)2020-11-25
T3 Platform software
K190273 (opens in new tab)510(k)2019-12-08
T3 Platform software
K163065 (opens in new tab)510(k)2017-05-26
T3 Software
K152258 (opens in new tab)510(k)2016-03-31
T3 Software
K151715 (opens in new tab)510(k)2015-10-29
T3 Software
K142732 (opens in new tab)510(k)2015-03-04
T3 Software
Isabel Healthcare
FDA decisions
No FDA decision cited in our research as of October 20, 2026.
Peer-reviewed
2 PubMed records name Isabel Healthcare.
- Cracking the code: a head-to-head comparison of expert clinicians and artificial intelligence in diagnosing rare diseases. (opens in new tab)
- Is language an issue? Accuracy of the German computerized diagnostic decision support system ISABEL and cross-validation with the English counterpart. (opens in new tab)
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | Etiometry Platform | Isabel Healthcare |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Not specified | Not specified |
| Founded | 2010 | 1999 |
| HQ | US | UK |
Scroll horizontally to see both columns.
Common questions
Open the full decision support comparison
Differential diagnosis, treatment guidance, drug interactions, evidence-grounded Q&A. The CDS landscape ranges from the UpToDate gold standard to physician-only OpenEvidence. We compared what clinicians actually use.
