Glass Health vs Isabel Healthcare
Glass bills by the month and Isabel by the year. Glass Pro is $90 per month and ad-free, so two months cost more than Isabel Standard at $149 per year. Lite is free and Starter is $20 per month, and both show sponsored content. An emergency physician who wants only a ranked differential with don't-miss flags would pay for a scribe and note writer that go unused, so Glass is the wrong fit there. A small athenahealth clinic is different. Glass Max, $200 per month, lists assisted EHR workflows for athenahealth, Epic, eClinicalWorks and Elation, plus the scribe and note drafting, while Isabel offers Cerner App Gallery availability, Epic info-button access and an API. Isabel's info-button access is a thinner link for that clinic. On paperwork, Glass advertises HIPAA-compliant infrastructure and BAAs for providers and organizations, while Isabel's pages are silent on HIPAA, SOC 2 and BAA. Accuracy data is thin on both sides. GLASS AI named the right diagnosis in 1 of 4 NEJM cases in a 2024 paper, and Isabel's top ten matched a case conference in 28% of 100 rare-disease patients in 2025.
Decision support · Reviewed November 1, 2026
Glass Health
by Glass Health · founded 2021
DDx plus literature-grounded A&P plus ambient scribe in one workflow.
Isabel Healthcare
by Isabel Healthcare · founded 1999
Differential-diagnosis generator with self-triage and educator products. The vendor says it is used in over 90 countries and 14 languages.
When to pick each one
Glass Health
- Max plan lists Epic, athenahealth, eCW and Elation workflows
- Scribe, cited differential and note drafting in one product
- Pro is $90 per month and ad-free
Isabel Healthcare
- Standard is $149 per year
- Red-flag list and a medication-cause check
- API since 2010 and a Cerner App Gallery listing
Score
Each row shows points earned of points available under the published rubric.
Glass Health
42of 100
Isabel Healthcare
35of 100
| Dimension | Glass Health | Isabel Healthcare | Difference |
|---|---|---|---|
| FDA clearance | 0 / 12 | 0 / 12 | 0 |
| HIPAA / SOC2 / BAA | 6 / 10 | 0 / 10 | +6 |
| EHR integrations (count) | 2.8 / 5.6 | 0 / 5.6 | +2.8 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 3.4 / 4.8 | 0 / 4.8 | +3.4 |
| Bidirectional write-back | 0 / 1.2 | 0 / 1.2 | 0 |
| Peer-reviewed papers | 8.4 / 21 | 14.7 / 21 | -6.3 |
| RCT / meta-analysis / systematic review | 0 / 9 | 0 / 9 | 0 |
| Funding & adoption signal | 8.4 / 12 | 6 / 12 | +2.4 |
| Pricing transparency | 2.5 / 2.5 | 2.5 / 2.5 | 0 |
| Years in market | 4.2 / 6 | 6 / 6 | -1.8 |
Scroll horizontally to see every column.
Pricing
Glass Health
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Lite | n/a | n/a | Limited scribing and clinical decision support. Carries ad sponsorships. |
| Starter | $20 | n/a | Carries ad sponsorships. |
| Pro | $90 | n/a | Most popular tier, ad-free. |
| Max | $200 | n/a | For clinics. EHR integration (Athena, Epic, eCW, Elation) is available only on this tier. |
Isabel Healthcare
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Standard | n/a | $149 | EUR 139 incl. VAT. 30-day free trial. |
| Premium | n/a | $199 | EUR 179 incl. VAT. Adds an LLM layer (English only). |
| Student / resident | n/a | $49 | Not available to EU students. 50% discount for listed emerging economies. |
| Institutional | n/a | n/a | Demo request, no public price. The API has been available since 2010. |
Evidence
Glass Health
FDA decisions
No FDA decision cited in our research as of October 26, 2026.
Peer-reviewed
1 PubMed record names Glass Health.
Community
1 post sourced: 0 positive, 1 neutral, 0 negative.
Isabel Healthcare
FDA decisions
No FDA decision cited in our research as of October 20, 2026.
Peer-reviewed
2 PubMed records name Isabel Healthcare.
- Cracking the code: a head-to-head comparison of expert clinicians and artificial intelligence in diagnosing rare diseases. (opens in new tab)
- Is language an issue? Accuracy of the German computerized diagnostic decision support system ISABEL and cross-validation with the English counterpart. (opens in new tab)
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | Glass Health | Isabel Healthcare |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Epic, athenahealth, eClinicalWorks, Elation | Not specified |
| Founded | 2021 | 1999 |
| HQ | US | UK |
Scroll horizontally to see both columns.
Common questions
Open the full decision support comparison
Differential diagnosis, treatment guidance, drug interactions, evidence-grounded Q&A. The CDS landscape ranges from the UpToDate gold standard to physician-only OpenEvidence. We compared what clinicians actually use.