Eko Health vs OpenEvidence
OpenEvidence goes to a verified US physician who wants cited answers over the medical literature, free for NPI-verified physicians and funded by ads, with a BAA and SOC 2 Type II stated on its security page. Eko goes to a clinician or clinic that wants a stethoscope with AI, and the AI sits behind a paid membership with a 14-day free trial.
OpenEvidence's peer-reviewed papers include a 2026 comparison with GPT-4o and Perplexity AI on diagnostic radiology board-style questions and a 2026 concordance study against the 2024 AAOS meniscal guideline. A November 2025 medRxiv pilot, not peer reviewed, scored accuracy at 31% for quick search and 39.5% for Deep Consult on subspecialty scenarios. A user on r/emergencymedicine reported a chest x-ray and pulmonary embolism error in September 2025.
Eko's PubMed hits include a 2019 Pediatric Cardiology evaluation of the Eko teleauscultation system and a 2025 Netherlands Heart Journal article on the CORE 500. The vendor claims 70+ publications, and its homepage line that providers using Eko are 2x more likely to detect heart disease is also its own claim.
Decision support · Reviewed November 2, 2026
Eko Health
by Eko Health
Digital stethoscopes and an AI membership that detect heart murmurs, AFib and low ejection fraction for clinicians.
OpenEvidence
by OpenEvidence · founded 2022
Free physician-only literature-grounded Q&A, 1M consults/day.
When to pick each one
Eko Health
- Digital stethoscope AI for murmurs and AFib
- 2019 field evaluation of the teleauscultation system
- Eko+ AI membership with a 14-day trial
OpenEvidence
- Free for NPI-verified physicians, ad-funded
- Security page states a BAA and SOC 2 Type II
- Cited answers over medical literature
Score
Each row shows points earned of points available under the published rubric.
Eko Health
48of 100
OpenEvidence
52of 100
| Dimension | Eko Health | OpenEvidence | Difference |
|---|---|---|---|
| FDA clearance | 12 / 12 | 0 / 12 | +12 |
| HIPAA / SOC2 / BAA | 10 / 10 | 0 / 10 | +10 |
| EHR integrations (count) | 0 / 5.6 | 0 / 5.6 | 0 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 0 / 4.8 | 0 / 4.8 | 0 |
| Bidirectional write-back | 0 / 1.2 | 0 / 1.2 | 0 |
| Peer-reviewed papers | 8.4 / 21 | 21 / 21 | -12.6 |
| RCT / meta-analysis / systematic review | 0 / 9 | 4.5 / 9 | -4.5 |
| Funding & adoption signal | 8.4 / 12 | 12 / 12 | -3.6 |
| Pricing transparency | 1.3 / 2.5 | 2.5 / 2.5 | -1.2 |
| Years in market | 0 / 6 | 4.2 / 6 | -4.2 |
Scroll horizontally to see every column.
Pricing
Eko Health
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| CORE 300 digital stethoscope | n/a | n/a | Sale price, list price $249 struck through on the product page. Sale end date not shown. |
| Eko+ | n/a | n/a | Required for Eko AI. Renews automatically for the year. 14-day free trial, downgrade to Free before day 14. |
| Enterprise (SENSORA, Eko Telehealth) | n/a | n/a | No public price. Contact sales. |
OpenEvidence
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Plan | n/a | n/a | Free for NPI-verified physicians (ad-funded). |
Evidence
Eko Health
FDA decisions
K261694 (opens in new tab)510(k)2026-07-23
CORE 300 Digital Stethoscope
K251494 (opens in new tab)510(k)2025-08-12
Eko Foundation Analysis Software with Transformers (EFAST)
K233409 (opens in new tab)510(k)2024-03-28
Eko Low Ejection Fraction Tool (ELEFT)
K233609 (opens in new tab)510(k)2024-03-28
CORE 500 Digital Stethoscope
K230111 (opens in new tab)510(k)2023-05-26
CORE 500 Digital Stethoscope
Show 5 more
K213794 (opens in new tab)510(k)2022-06-29
Eko Murmur Analysis Software (EMAS)
K200776 (opens in new tab)510(k)2020-04-06
Eko CORE
K192004 (opens in new tab)510(k)2020-01-15
Eko Analysis Software
K170874 (opens in new tab)510(k)2017-05-19
Eko Model E5 System (EME5), Eko DUO
K151319 (opens in new tab)510(k)2015-08-28
Eko Electronic Stethoscope System
Peer-reviewed
1 PubMed record names Eko Health.
OpenEvidence
FDA decisions
No FDA decision cited in our research as of October 20, 2026.
Peer-reviewed
5 PubMed records name OpenEvidence.
- Performance of Large Language Models on Diagnostic Radiology Board-Style Questions: A Comparative Evaluation of GPT-4o, Perplexity AI, and OpenEvidence. (opens in new tab)
- OpenEvidence. (opens in new tab)
- Concordance of ChatGPT, Gemini, Claude, and OpenEvidence with the 2024 AAOS guidelines on acute isolated meniscal pathology. (opens in new tab)
Community
20 posts sourced: 3 positive, 14 neutral, 3 negative.
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | Eko Health | OpenEvidence |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Not specified | Not specified |
| Founded | n/a | 2022 |
| HQ | US | US |
Scroll horizontally to see both columns.
Common questions
Open the full decision support comparison
Differential diagnosis, treatment guidance, drug interactions, evidence-grounded Q&A. The CDS landscape ranges from the UpToDate gold standard to physician-only OpenEvidence. We compared what clinicians actually use.