MedAI Verdict
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Epocrates vs Micromedex

Micromedex is sold to institutions, quoted per organization with no public price. A hospital pharmacy or toxicology service that licenses it gets Poisindex toxicology, RED BOOK pricing, NeoFax and pediatric content, IV compatibility and, since September 2025, an AI search that returns cited answers. Merative says it validated that search through internal testing, external clinician validation and real-world testing, and publishes no independent accuracy data. It also claims the 2026 Best in KLAS ranking for point-of-care drug reference. A toxicology service gets no matching content from Epocrates, whose epocrates+ page lists none, so Epocrates is out for that buyer. The Epocrates buyer is a resident or attending paying personally, at $24.99 per month or $179.99 per year, with a group plan for teams. In a 2016 count of detected interactions, Epocrates reached 250 of 400 and Micromedex 236, on versions of that year.

Drug info · Reviewed November 1, 2026

Epocrates logo

Epocrates

by Epocrates (athenahealth) · founded 1998

Drug reference app with interaction checks, calculators, disease guidance and a beta AI Assist.

Micromedex logo

Micromedex

by Merative

Drug reference with interaction checking, IV compatibility, toxicology and RED BOOK pricing, plus AI-powered search since September 2025.

When to pick each one

Epocrates

  • Individual plan, $24.99 per month or $179.99 per year
  • Group plan for teams and residents
Read the full Epocrates review

Micromedex

  • Poisindex toxicology and RED BOOK pricing content
  • AI search with cited answers since September 2025
  • Institutional subscription, quoted per organization
Read the full Micromedex review

Score

Each row shows points earned of points available under the published rubric.

Epocrates

74of 100

Top-ranked

Micromedex

52of 100

Solid choice
Score by dimension for Epocrates and Micromedex
DimensionEpocratesMicromedexDifference
EHR integrations (count)0 / 4.20 / 4.20
Top-3 EHR coverage (Epic / Oracle / Athena)0 / 2.40 / 2.40
Peer-reviewed papers14.7 / 2114.7 / 210
RCT / meta-analysis / systematic review3 / 63 / 60
Funding & adoption signal15.6 / 15.610.9 / 15.6+4.7
Pricing transparency6 / 63 / 6+3
Years in market6 / 60 / 6+6

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How scores are computed

Pricing

Epocrates

TierMonthlyAnnualNotes
epocrates+, monthly$24.99n/aCancel anytime.
epocrates+, yearlyn/a$179.99The page says Save 40% when subscribing annually. Trial and refund terms are not stated.

Micromedex

TierMonthlyAnnualNotes
Institutional subscriptionn/an/aNo public price, quoted per organization. No current individual subscription was found.

Compliance and integrations

Documented from each vendor’s own pages.

SpecEpocratesMicromedex
Free tierNo / unverifiedNo / unverified
HIPAANo / unverifiedNo / unverified
SOC 2 Type IINo / unverifiedNo / unverified
EHR integrationsNot specifiedNot specified
Founded1998n/a
HQUSn/a

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Common questions

Open the full drug info comparison

Drug references (Lexidrug, Micromedex, Epocrates) and interaction checkers (Drugs.com, Medscape). Built for the clinician at the point of care.