Glass Health vs Sepsis ImmunoScore
A hospital sepsis program evaluates Prenosis. Sepsis ImmunoScore holds FDA De Novo DEN230036, decision date April 2024. It sorts adults with suspected sepsis in the ED or hospital into four risk bands from up to 22 EHR parameters, and the vendor says it is not validated in the ICU or on labor and delivery units. Pricing is by demo or contact only. Its papers include a vendor-run development and validation study in NEJM AI and further vendor-listed papers in Diagnostics and JAMIA Open. A hospital sepsis program and an individual physician do not shop for the same tool.
An individual physician evaluates Glass Health, an ambient scribe with cited differentials and must-not-miss flags. The vendor claims no FDA status. A 2024 paper in The Neurologist ran four NEJM cases through Glass, and the tool got 1 right while ChatGPT-4 got 0 and a diagnostic generator got all four. The comparison was tiny and non-randomized.
Decision support · Reviewed November 2, 2026
Glass Health
by Glass Health · founded 2021
DDx plus literature-grounded A&P plus ambient scribe in one workflow.
Sepsis ImmunoScore
by Prenosis
AI sepsis risk score from up to 22 EHR parameters for adults with suspected sepsis in the ED or hospital, FDA De Novo authorized.
When to pick each one
Glass Health
- Differential diagnosis with must-not-miss flags
- Four-case NEJM test, 1 correct versus 0 for ChatGPT-4
Sepsis ImmunoScore
- FDA De Novo DEN230036, April 2024
- Sepsis score for adults in the ED or hospital
Score
Each row shows points earned of points available under the published rubric.
Glass Health
42of 100
Sepsis ImmunoScore
37of 100
| Dimension | Glass Health | Sepsis ImmunoScore | Difference |
|---|---|---|---|
| FDA clearance | 0 / 12 | 12 / 12 | -12 |
| HIPAA / SOC2 / BAA | 6 / 10 | 0 / 10 | +6 |
| EHR integrations (count) | 2.8 / 5.6 | 0 / 5.6 | +2.8 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 3.4 / 4.8 | 0 / 4.8 | +3.4 |
| Bidirectional write-back | 0 / 1.2 | 0 / 1.2 | 0 |
| Peer-reviewed papers | 8.4 / 21 | 14.7 / 21 | -6.3 |
| RCT / meta-analysis / systematic review | 0 / 9 | 0 / 9 | 0 |
| Funding & adoption signal | 8.4 / 12 | 3 / 12 | +5.4 |
| Pricing transparency | 2.5 / 2.5 | 1.3 / 2.5 | +1.3 |
| Years in market | 4.2 / 6 | 0 / 6 | +4.2 |
Scroll horizontally to see every column.
Pricing
Glass Health
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Lite | n/a | n/a | Limited scribing and clinical decision support. Carries ad sponsorships. |
| Starter | $20 | n/a | Carries ad sponsorships. |
| Pro | $90 | n/a | Most popular tier, ad-free. |
| Max | $200 | n/a | For clinics. EHR integration (Athena, Epic, eCW, Elation) is available only on this tier. |
Sepsis ImmunoScore
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. Demo or contact only. |
Evidence
Glass Health
FDA decisions
No FDA decision cited in our research as of October 26, 2026.
Peer-reviewed
1 PubMed record names Glass Health.
Community
1 post sourced: 0 positive, 1 neutral, 0 negative.
Sepsis ImmunoScore
FDA decisions
DEN230036 (opens in new tab)De Novo2024-04-02
Sepsis ImmunoScore
Peer-reviewed
2 PubMed records name Sepsis ImmunoScore.
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | Glass Health | Sepsis ImmunoScore |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Epic, athenahealth, eClinicalWorks, Elation | Not specified |
| Founded | 2021 | n/a |
| HQ | US | US |
Scroll horizontally to see both columns.
Common questions
Open the full decision support comparison
Differential diagnosis, treatment guidance, drug interactions, evidence-grounded Q&A. The CDS landscape ranges from the UpToDate gold standard to physician-only OpenEvidence. We compared what clinicians actually use.