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PrecisePK vs UpToDate Lexidrug

A hospital pharmacy department is the buyer both could plausibly sign. Lexidrug's interactive tools include drug interaction analysis, drug identification and medical calculations, and its dosing guidance is organized by patient group, including renal and hepatic impairment, obesity, pediatric, neonatal, geriatric and pregnancy. Its enterprise tier has no public price and a contact form. PrecisePK builds an individual dose from one blood level. It says it complies with the 2020 ASHP and IDSA vancomycin guidelines, a vendor claim. It integrates into Wolters Kluwer's Sentri7 and names Epic and Cerner (Oracle Health).

For a pharmacy with one budget line and no dedicated vancomycin program, PrecisePK loses. Its page names vancomycin and busulfan with other drugs unnamed, while Lexidrug's content spans pharmacy, nursing and dentistry.

Drug info · Reviewed November 2, 2026

PrecisePK logo

PrecisePK

by PrecisePK

Bayesian model-informed precision dosing software that calculates individualized drug regimens from serum levels, including vancomycin.

UpToDate Lexidrug logo

UpToDate Lexidrug

by Wolters Kluwer

Drug reference with interaction analysis, dosing guidance and IV compatibility, from UpToDate (formerly Lexicomp).

When to pick each one

PrecisePK

  • Individual dose from one blood level
  • Integrates with Wolters Kluwer's Sentri7
Read the full PrecisePK review

UpToDate Lexidrug

  • Dosing guidance by renal, hepatic and age group
  • Toxicology and pharmacogenomic content
Read the full UpToDate Lexidrug review

Score

Each row shows points earned of points available under the published rubric.

PrecisePK

55of 100

Solid choice

UpToDate Lexidrug

30of 100

Competitive
Score by dimension for PrecisePK and UpToDate Lexidrug
DimensionPrecisePKUpToDate LexidrugDifference
EHR integrations (count)1.3 / 4.20 / 4.2+1.3
Top-3 EHR coverage (Epic / Oracle / Athena)1.7 / 2.40 / 2.4+1.7
Peer-reviewed papers21 / 210 / 21+21
RCT / meta-analysis / systematic review3 / 60 / 6+3
Funding & adoption signal3.9 / 15.615.6 / 15.6-11.7
Pricing transparency3 / 63 / 60
Years in market0 / 60 / 60

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How scores are computed

Pricing

PrecisePK

TierMonthlyAnnualNotes
Enterprisen/an/aNo public price. Homepage advertises "Free for 60 days" trial; the trial page gives no length or terms.

UpToDate Lexidrug

TierMonthlyAnnualNotes
Enterprisen/an/aNo public price, contact form only. Personal subscriptions are also sold (mobile app and store.uptodate.com), but the current personal price is not confirmed.

Compliance and integrations

Documented from each vendor’s own pages.

SpecPrecisePKUpToDate Lexidrug
Free tierYesNo / unverified
HIPAAYesNo / unverified
SOC 2 Type IIYesNo / unverified
EHR integrationsEpic, CernerNot specified
Foundedn/an/a
HQUSNL

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Common questions

Open the full drug info comparison

Drug references (Lexidrug, Micromedex, Epocrates) and interaction checkers (Drugs.com, Medscape). Built for the clinician at the point of care.