PrecisePK vs UpToDate Lexidrug
A hospital pharmacy department is the buyer both could plausibly sign. Lexidrug's interactive tools include drug interaction analysis, drug identification and medical calculations, and its dosing guidance is organized by patient group, including renal and hepatic impairment, obesity, pediatric, neonatal, geriatric and pregnancy. Its enterprise tier has no public price and a contact form. PrecisePK builds an individual dose from one blood level. It says it complies with the 2020 ASHP and IDSA vancomycin guidelines, a vendor claim. It integrates into Wolters Kluwer's Sentri7 and names Epic and Cerner (Oracle Health).
For a pharmacy with one budget line and no dedicated vancomycin program, PrecisePK loses. Its page names vancomycin and busulfan with other drugs unnamed, while Lexidrug's content spans pharmacy, nursing and dentistry.
Drug info · Reviewed November 2, 2026

PrecisePK
by PrecisePK
Bayesian model-informed precision dosing software that calculates individualized drug regimens from serum levels, including vancomycin.
UpToDate Lexidrug
by Wolters Kluwer
Drug reference with interaction analysis, dosing guidance and IV compatibility, from UpToDate (formerly Lexicomp).
When to pick each one
PrecisePK
- Individual dose from one blood level
- Integrates with Wolters Kluwer's Sentri7
UpToDate Lexidrug
- Dosing guidance by renal, hepatic and age group
- Toxicology and pharmacogenomic content
Score
Each row shows points earned of points available under the published rubric.
PrecisePK
55of 100
UpToDate Lexidrug
30of 100
| Dimension | PrecisePK | UpToDate Lexidrug | Difference |
|---|---|---|---|
| EHR integrations (count) | 1.3 / 4.2 | 0 / 4.2 | +1.3 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 1.7 / 2.4 | 0 / 2.4 | +1.7 |
| Peer-reviewed papers | 21 / 21 | 0 / 21 | +21 |
| RCT / meta-analysis / systematic review | 3 / 6 | 0 / 6 | +3 |
| Funding & adoption signal | 3.9 / 15.6 | 15.6 / 15.6 | -11.7 |
| Pricing transparency | 3 / 6 | 3 / 6 | 0 |
| Years in market | 0 / 6 | 0 / 6 | 0 |
Scroll horizontally to see every column.
Pricing
PrecisePK
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. Homepage advertises "Free for 60 days" trial; the trial page gives no length or terms. |
UpToDate Lexidrug
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price, contact form only. Personal subscriptions are also sold (mobile app and store.uptodate.com), but the current personal price is not confirmed. |
Evidence
PrecisePK
Peer-reviewed
5 PubMed records name PrecisePK.
- Predictive Performance of Bayesian Dosing Software for Vancomycin in Intensive Care Unit Patients. (opens in new tab)
- Model-Informed Precision Dosing of Vancomycin in Vietnamese Children: Innovative Midpoint Concentration Monitoring Using 2 Bayesian Programs. (opens in new tab)
- [Free online software tools for precision dosing of vancomycin, and other drugs]. (opens in new tab)
UpToDate Lexidrug
No FDA decision, peer-reviewed study or community post in our record.
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | PrecisePK | UpToDate Lexidrug |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Epic, Cerner | Not specified |
| Founded | n/a | n/a |
| HQ | US | NL |
Scroll horizontally to see both columns.
Common questions
Open the full drug info comparison
Drug references (Lexidrug, Micromedex, Epocrates) and interaction checkers (Drugs.com, Medscape). Built for the clinician at the point of care.
