DoseMeRx vs UpToDate Lexidrug
Lexidrug, formerly Lexicomp, comes from Wolters Kluwer with interaction analysis, Trissel's IV compatibility, dosing guidance by renal and hepatic impairment, obesity, pediatric and neonatal use, toxicology and an offline mobile app. Wolters Kluwer sells it under the UpToDate brand. Enterprise buyers use a contact form, and personal subscriptions are sold through Wolters Kluwer's online store.
DoseMeRx covers dose individualization from measured concentrations, with 24/7 support and a staged set-up journey, and the vendor says it is the only HITRUST CSF certified Bayesian dosing platform.
A hospital pharmacy that needs a reference for interactions, IV compatibility and renal and hepatic dosing buys Lexidrug. For a pharmacy that needs Bayesian vancomycin AUC dosing from patient levels and is looking at Lexidrug, Lexidrug loses, since its page lists dosing by patient group and DoseMeRx states concentration-based individualization.
Drug info · Reviewed November 2, 2026

DoseMeRx
by DoseMe
Bayesian model-informed dosing platform for high-risk medications such as vancomycin and aminoglycosides, used by hospital pharmacists.
UpToDate Lexidrug
by Wolters Kluwer
Drug reference with interaction analysis, dosing guidance and IV compatibility, from UpToDate (formerly Lexicomp).
When to pick each one
DoseMeRx
- 24/7 support and staged set-up journey
- Home infusion and analytics modules
UpToDate Lexidrug
- Former Lexicomp with Trissel's IV compatibility
- Mobile app with offline download
- Enterprise contract or personal subscription
Score
Each row shows points earned of points available under the published rubric.
DoseMeRx
35of 100
UpToDate Lexidrug
30of 100
| Dimension | DoseMeRx | UpToDate Lexidrug | Difference |
|---|---|---|---|
| EHR integrations (count) | 0 / 4.2 | 0 / 4.2 | 0 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 0 / 2.4 | 0 / 2.4 | 0 |
| Peer-reviewed papers | 14.7 / 21 | 0 / 21 | +14.7 |
| RCT / meta-analysis / systematic review | 0 / 6 | 0 / 6 | 0 |
| Funding & adoption signal | 3.9 / 15.6 | 15.6 / 15.6 | -11.7 |
| Pricing transparency | 3 / 6 | 3 / 6 | 0 |
| Years in market | 0 / 6 | 0 / 6 | 0 |
Scroll horizontally to see every column.
Pricing
DoseMeRx
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price. Only a demo request form is linked. |
UpToDate Lexidrug
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | n/a | n/a | No public price, contact form only. Personal subscriptions are also sold (mobile app and store.uptodate.com), but the current personal price is not confirmed. |
Evidence
DoseMeRx
Peer-reviewed
4 PubMed records name DoseMeRx.
- [Free online software tools for precision dosing of vancomycin, and other drugs]. (opens in new tab)
- Evaluation of two model-based Bayesian approaches for vancomycin dosing in general hospitalized patients. (opens in new tab)
- Implementation of Vancomycin Therapeutic Monitoring Guidelines: Focus on Bayesian Estimation Tools in Neonatal and Pediatric Patients. (opens in new tab)
UpToDate Lexidrug
No FDA decision, peer-reviewed study or community post in our record.
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | DoseMeRx | UpToDate Lexidrug |
|---|---|---|
| Free tier | ||
| HIPAA | ||
| SOC 2 Type II | ||
| EHR integrations | Not specified | Not specified |
| Founded | n/a | n/a |
| HQ | US | NL |
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Common questions
Open the full drug info comparison
Drug references (Lexidrug, Micromedex, Epocrates) and interaction checkers (Drugs.com, Medscape). Built for the clinician at the point of care.
