Clinical Decision Support
Zio vs PMcardio Queen of Hearts
Scores are legacy evidence and documentation scores, not product-performance ratings. How it is computed
Zio scores 56 of 100 (Solid choice), PMcardio Queen of Hearts 59 (Solid choice). PMcardio Queen of Hearts lists a public price, Zio is quote only.
Decision support · Reviewed November 5, 2026
On this page
Zio
by iRhythm Technologies · founded 2006
Zio ECG patch service: a deep-learning algorithm flags arrhythmias, cardiac technicians validate them, and a physician report follows.
PMcardio Queen of Hearts
by Powerful Medical · founded 2017
FDA De Novo authorized AI ECG model that flags STEMI and STEMI-equivalent occlusion MI on any 12-lead ECG, in the PMcardio app and in health-system STEMI pathways.
Score
Each row shows points earned of points available under the published rubric.
Zio
PMcardio Queen of Hearts
| Dimension | Zio | PMcardio Queen of Hearts | Difference |
|---|---|---|---|
| FDA clearance | 12 / 12 | 12 / 12 | 0 |
| HIPAA / SOC2 / BAA | 0 / 10 | 10 / 10 | -10 |
| EHR integrations (count) | 0 / 5.6 | 0 / 5.6 | 0 |
| Top-3 EHR coverage (Epic / Oracle / Athena) | 0 / 4.8 | 0 / 4.8 | 0 |
| Bidirectional write-back | 0 / 1.2 | 0 / 1.2 | 0 |
| Peer-reviewed papers | 14.7 / 21 | 8.4 / 21 | +6.3 |
| RCT / meta-analysis / systematic review | 4.5 / 9 | 4.5 / 9 | 0 |
| Funding & adoption signal | 8.4 / 12 | 6 / 12 | +2.4 |
| Pricing transparency | 1.3 / 2.5 | 2.5 / 2.5 | -1.2 |
| Years in market | 6 / 6 | 6 / 6 | 0 |
Scroll horizontally to see every column.
Pricing
Zio
| Tier | Monthly | Annual | Notes |
|---|---|---|---|
| Enterprise | Not stated | Not stated | No public price. |
PMcardio Queen of Hearts
| Tier | Billing period | Price | Notes |
|---|---|---|---|
| Free | per month | Free | 5 ECG reports per month, no credit card. The pricing page defaults to the Slovak region and says prices vary by country. |
| Individuals | per user per month | EUR 10 | 10 EUR per month, 17 percent off billed yearly. 50 ECGs per month, Queen of Hearts, LVsense, ECGxplain and 36 core diagnostics, mobile app only, 30-day report history. Paid through the app store. Slovak-region price; the page says prices vary by country. |
| Teams | per year | EUR 2,610 | 2,610 EUR per year for 10 users (22 EUR per user per month, billed yearly), scalable to 50 users, 1,000 ECGs per month, web app, unlimited report history, US or EU data centre, onboarding session. Invoiced. Slovak-region price. |
| Organizations | Not stated | Not stated | No public price. Unlimited reports, users and locations, HL7/XML and EHR integration, AI-powered STEMI pathway, dedicated data residency and SLA. Contact sales. |
Verified November 5, 2026 from powerfulmedical.com (opens in new tab).
Evidence
Zio
FDA decisions
K252859 (opens in new tab)510(k)2026-05-29
ZEUS Platform (FG0501US, DQK)
K243650 (opens in new tab)510(k)2025-08-15
Zio monitor (DFG0001)
K240177 (opens in new tab)510(k)2024-10-30
Zio AT device (A100A1001, DSI)
K240029 (opens in new tab)510(k)2024-10-21
Zio AT device (A100A1001, QYX)
K222389 (opens in new tab)510(k)2023-02-15
ZEUS System
Show 13 more
K213409 (opens in new tab)510(k)2022-07-19
ZEUS System (Zio Watch)
K202359 (opens in new tab)510(k)2021-05-21
Zio Monitor
K202527 (opens in new tab)510(k)2021-05-21
ZEUS System
K190593 (opens in new tab)510(k)2019-08-23
Zio XT ECG Monitoring System, Zio AT
K181502 (opens in new tab)510(k)2018-08-29
Zio AT ECG Monitoring System, ZEUS System
K163512 (opens in new tab)510(k)2017-06-02
Zio AT ECG Monitoring System
K143513 (opens in new tab)510(k)2015-06-19
ZIO SR ECG Monitoring Service
K142681 (opens in new tab)510(k)2014-11-21
ZEUS System
K121319 (opens in new tab)510(k)2012-07-18
ZIO PATCH
K113862 (opens in new tab)510(k)2012-02-06
ZIO PATCH
K091075 (opens in new tab)510(k)2009-07-21
ZEUS (ZIO ECG UTILIZATION SERVICE) SYSTEM
K090363 (opens in new tab)510(k)2009-05-08
ZIO PATCH Z100
K081471 (opens in new tab)510(k)2008-06-24
ECARD AND CCARD
Peer-reviewed
5 PubMed records name Zio.
- Physical activity cut-points for older adults using the Zio XT onboard accelerometer. (opens in new tab)
- Validation of a Zio XT Patch Accelerometer for the Objective Assessment of Physical Activity in the Atherosclerosis Risk in Communities (ARIC) Study. (opens in new tab)
- Zio® XT Patches in Pediatrics During the COVID-19 Pandemic: Comparisons Between In-Person and Mail-Home Application. (opens in new tab)
PMcardio Queen of Hearts
FDA decisions
DEN250044 (opens in new tab)De Novo2026-09-03
STEMI AI ECG Model
Peer-reviewed
6 PubMed records name PMcardio Queen of Hearts.
- Electrocardiographic diagnostic possibilities for atrial fibrillation using artificial intelligence: Differentiation from sinus rhythm and other arrhythmias with the PMcardio app in COVID-19 patients. (opens in new tab)
- Bifascicular Block Associated With Myocardial Infarction: A Marker of Proximal Left Anterior Descending Artery Occlusion Confirmed by the Artificial Intelligence-Based Smartphone App Queen of Hearts. (opens in new tab)
- Accuracy of cath lab activation decisions for STEMI-equivalent and mimic ECGs: Physicians vs. AI (Queen of Hearts by PMcardio). (opens in new tab)
Compliance and integrations
Documented from each vendor’s own pages.
| Spec | Zio | PMcardio Queen of Hearts |
|---|---|---|
| Free tier | No / unverified | Yes |
| HIPAA | No / unverified | Yes |
| SOC 2 Type II | No / unverified | Yes |
| EHR integrations | Not stated | Not stated |
| Founded | 2006 | 2017 |
| HQ | US | US |
Scroll horizontally to see both columns.
Common questions
Open the full decision support comparison
Differential diagnosis, treatment guidance, drug interactions, evidence-grounded Q&A. The CDS landscape ranges from the UpToDate gold standard to physician-only OpenEvidence. We compared what clinicians actually use.
See all decision support