AI Pathology
Vesta alternatives
13 tools that we compared head to head with Vesta in a written verdict. Each row says who the tool suits, according to that verdict, and links to the full comparison.
The list is not a ranking. Tools in the same category come first, then every group is in alphabetical order. A tool that is no longer sold is left out.
aetherAI
Hospital digital pathology planning and implementation; iSO 13485 and ISO 27001 certificates listed
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Aiforia
CE-IVD Prostate Cancer Biopsy AI; cribriform Gleason 4 and PNI models, IVDR Class C per register
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Artera
mHSPC version of the prostate test; vendor claims Medicare and commercial coverage
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Caris Life Sciences
PMA-approved MI Cancer Seek, November 2024; companion-diagnostic claims for Piqray, Vectibix and Keytruda
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Freenome
Qualitative blood test, colonoscopy after a positive; pMA-approved, P250029
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GRAIL
Classifier on cell-free DNA methylation; predicts tissue of origin for a cancer signal
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Ibex Medical Analytics
Prostate Detect cleared, K241232, January 2025; open API to scanners, image management, LIS
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Indica Labs HALO AI
HALO AI classifier tuned by example; hALO Prostate AI is CE-IVD marked
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PathAI AISight
AISight Dx cleared, K243391, June 2025; roche partnership since 2021
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Proscia Concentriq
FDA 510(k)s for FFPE primary diagnosis, Hamamatsu and Leica scanners; sOC 2 Type II announced December 2025
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Full comparisonSectra Pathology
Two FDA 510(k)s for the Digital Pathology Module; third-party AI apps on one Amplifier contract
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Tempus Digital Pathology
Paige Prostate Detect, FDA De Novo and CE-IVDR; fullFocus viewer holds two 510(k)s
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Visiopharm
CE-IVD apps for ER, PR, HER2 and Ki-67; rUO image-analysis platform for pharma and academia
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